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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ivm</journal-id><journal-title-group><journal-title xml:lang="ru">Международный вестник ветеринарии</journal-title><trans-title-group xml:lang="en"><trans-title>International Journal of Veterinary Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-2419</issn><publisher><publisher-name>SpbGUVM Publishing House</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52419/issn2072-2419.2022.4.357</article-id><article-id custom-type="elpub" pub-id-type="custom">ivm-1011</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>БИОХИМИЯ, МОРФОЛОГИЯ, ФИЗИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BIOCHEMISTRY, ANATOMY, PHYSIOLOGY</subject></subj-group></article-categories><title-group><article-title>Исследование особенностей обмена веществ у овец романовской породы на протяжении периода лактации в условиях промышленных комплексов Северо-Западного региона России</article-title><trans-title-group xml:lang="en"><trans-title>Research of romanov sheep metabolism characteristics over the period of lactation in estations of North-Western region</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Курилова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kurilova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> аспирант кафедры биохимии и физиологии </p></bio><bio xml:lang="en"><p> post-graduate student, Department of biochemistry and physiology </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карпенко</surname><given-names>Л. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Karpenko</surname><given-names>L. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p> д.биол.н., проф., зав. каф. биохимии и физиологии </p></bio><bio xml:lang="en"><p>doctor of biological science, professor, head of department of biochemistry and physiology </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Максимов</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Maximov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.биол.н., проф., проф. каф. физиологии, фармакологии и токсикологии им. А.Н. Голикова и И.Е. Мозгова </p></bio><bio xml:lang="en"><p>Doctor of Biological Sciences, Professor, Professor of the Department of Physiology, Pharmacology and Toxicology named after A. N. Golikov andI. E. Mozgov</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Махнин</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Makhnin</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> студент 5-го курса факультета ветеринарной медицины</p></bio><bio xml:lang="en"><p> student of veterinary faculty </p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Санкт-Петербургский государственный университет ветеринарный медицины»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint-Petersburg State University of Veterinary Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Московская государственная академия ветеринарной медицины и биотехнологий - МВА им. К.И. Скрябина»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow State Academy of Veterinary Medicine and Biotechnology – MBA named after K. I. Scriabin</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>02</day><month>02</month><year>2023</year></pub-date><volume>0</volume><issue>4</issue><fpage>357</fpage><lpage>363</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Курилова А.А., Карпенко Л.Ю., Максимов В.И., Махнин И.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Курилова А.А., Карпенко Л.Ю., Максимов В.И., Махнин И.А.</copyright-holder><copyright-holder xml:lang="en">Kurilova A.A., Karpenko L.Y., Maximov V.I., Makhnin I.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vetjournal.spbguvm.ru/jour/article/view/1011">https://vetjournal.spbguvm.ru/jour/article/view/1011</self-uri><abstract><p>Селен является незаменимым микроэлементом в рационе сельскохозяйственных животных. Селен входит в состав ферментов антиоксидантной системы, препятствуя разрушению свободными радикалами клеток организма. Обеспеченность селеном сильно варьируется в связи с обилием биогеохимических территорий. Так на территории Северо-Западного региона России отмечается крайне низкое содержание селена в почвах и растениях. В ходе проведенного исследования было установлено, что концентрация селена в растениях пастбищ варьирует в диапазоне от 0,059 до 0,067 мкг/кг при оптимальном значении от 0,1 мг/кг. При исследовании морфологических и биохимических параметров крови овец романовской породы на протяжении периода лактации установлено, что у животных концентрация гемоглобина, количество эритроцитов, концентрация общего белка и альбуминов находится ниже референсных значений. Количество эритроцитов также увеличивалось. На 100-е сутки количество эритроцитов было выше на 7,78% в сравнении с 30-ыми сутками и на 14,59% в сравнении с 10-ыми сутками с момента начала лактации. Отмечалось увеличение концентрации общего белка за счет фракции альбуминов. На 100-е сутки концентрация общего белка была выше на 15,29% в сравнении с 10-ыми сутками и на 9,46% в сравнении с 30-ыми сутками с момента начала лактации. На 100-е сутки с момента начала лактации концентрация гемоглобина была выше на 19,07% в сравнении с 10-ыми сутками с момента начала лактации и на 10,73% в сравнении с 30-ыми сутками с момента начала лактации. На более поздних сроках лактации наблюдается увеличение выше названных показателей до нижней границы нормы, что свидетельствует о нарушении обмена веществ в организме.</p></abstract><trans-abstract xml:lang="en"><p>Selenium is an essential trace element in the diet of farm animals. Selenium is a part of the antioxidant enzymes, preventing the free radicals cell destruction. Selenium availability varies greatly due to the great number of biogeochemical territories. The NorthWestern region of Russia is a territory with selenium deficiency in soils and plants. In this study, it was found that the concentration of selenium in pasture plants was in the range from 0,059 to 0,067 µg /kg with an optimal value of 0,1 mg/kg. It was found that the concentration of hemoglobin, the number of red blood cells, the concentration of total protein and albumins in blood of Romanov sheep over the period of lactation was below the reference values. The number of red blood cells also increased. On the 100th day, the number of red blood cells was higher by 7.78% compared to the 30th day and by 14.59% compared to the 10th day since the beginning of lactation. There was an increase in the concentration of total protein due to the albumin fraction. On the 100th day, the total protein concentration was 15.29% higher compared to the 10th day and 9.46% higher compared to the 30th day since the beginning of lactation. On the 100th day from the start of lactation, the hemoglobin concentration was 19.07% higher compared to the 10th day from the start of lactation and 10.73% higher compared to the 30th day from the start of lactation. It was marked that those parameters had got higher to the low reference limit at the late period of lactation. This tendency could be the effect of metabolic imbalance and selenium deficiency in sheep diet.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>селен</kwd><kwd>овцы</kwd><kwd>микроэлементозы</kwd><kwd>глутатионпероксидаза</kwd><kwd>лактация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>selenium</kwd><kwd>sheep</kwd><kwd>microelementosis</kwd><kwd>glutathione peroxidase</kwd><kwd>lactation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Зверев, А.А. Статистические методы в биологии: учебно-методическое пособие / А.А. Зверев, Т.Л. 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