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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ivm</journal-id><journal-title-group><journal-title xml:lang="ru">Международный вестник ветеринарии</journal-title><trans-title-group xml:lang="en"><trans-title>International Journal of Veterinary Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-2419</issn><publisher><publisher-name>SpbGUVM Publishing House</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52419/issn2072-2419.2023.4.227</article-id><article-id custom-type="elpub" pub-id-type="custom">ivm-1177</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>БИОХИМИЯ, АНАТОМИЯ, ФИЗИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BIOCHEMISTRY, ANATOMY, PHYSIOLOGY</subject></subj-group></article-categories><title-group><article-title>Характеристики эритропоэза у свиноматок в различные периоды  производственного цикла</article-title><trans-title-group xml:lang="en"><trans-title>Characteristics of erythropoiesis in sows during different periods of the  production cycle</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6774-4288</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воронина</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Voronina</surname><given-names>О. А.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. биол.наук, ст. науч. сотр. гр. аналитической биохимии</p></bio><bio xml:lang="en"><p>Candidate of Biological Sciences, Senior Researcher of the Analytical  Biochemistry  Group</p></bio><email xlink:type="simple">voroninaok-senia@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1533-8680</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайцев</surname><given-names>С. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaitsev</surname><given-names>S. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р хим. наук, д-р биол. наук, вед. науч.  сотр., руководитель  группы  аналитической  биохимии</p></bio><bio xml:lang="en"><p>Doctor of Chemical  Sciences,  Doctor of  Biological Sciences,  leading  researcher,  Head  of  the Analytical Biochemistry  Group</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное научное учреждение «Федеральный исследовательский центр животноводства - ВИЖ имени академика Л.К. Эрнста»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Research Center for Animal Husbandry named after Academy Member L.K. Ernst</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>13</day><month>12</month><year>2023</year></pub-date><volume>0</volume><issue>4</issue><fpage>227</fpage><lpage>235</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Воронина О.А., Зайцев С.Ю., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Воронина О.А., Зайцев С.Ю.</copyright-holder><copyright-holder xml:lang="en">Voronina О.А., Zaitsev S.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vetjournal.spbguvm.ru/jour/article/view/1177">https://vetjournal.spbguvm.ru/jour/article/view/1177</self-uri><abstract><p>Тактика периодического контроля гематологии свиноматок позволяет  своевременно  принимать  меры  по  профилактике  состояния анемии,  которое  неизбежно  возникает,  поскольку  направленный отбор и селекция промышленных пород нацелены на многоплодие, что повышает риски возникновения анемии в период супоросности и подсосного периода. При периодическом и регулярном контроле, возможно выведение индивидуальных референтных интервалов гематологических показателей для конкретного животного и контроля отклика на компенсаторные мероприятия от чего напрямую зависит выход жизнеспособных поросят и их выживаемость. Целью данного исследования стало изучение числа эритроцитов, уровня гемоглобина, гематокрита, среднего объема эритроцитов и эритроцитарных индексов в зависимости от производственного цикла свиноматки. Группы были сформированы из свиноматок на 80 день супоросности (1 группа, n=5), после опороса (2 группа, n=5) и перед отъемом поросят (3 группа, n=5). Анализатор Vet ABCTM (Horiba Medical Польша) был использован. Подсчет ретикулоцитов методом «суправитальной окраски» раствором «бриллиантового крезилового синего». Статистическая обработка в программе «Microsoft Exсel» (пакет «Анализ данных»), оценка достоверности различий на базе U критерия Манна—Уитни. В результате установлено, что средний объем эритроцита увеличивается со снижением их числа и  концентрации гемоглобина, что вполне закономерно и  свидетельствует о регенераторном ответе с появлением в крови ретикулоцитов. Коэффициент корреляции между эритроцитами и средним объемом эритроцита составил r=-0.53 (r2=0.28, p=0.01), между средним объемом эритроцита и ретикулоцитами r=-0.50 (r2=0.25, p=0.05). Достоверных различий среди групп по ретикулоцитам и среднему объему эритроцита не выявлено. Динамика и интенсивность регенерации умеренная во всех трех группах.</p></abstract><trans-abstract xml:lang="en"><p>The tactics of periodic monitoring of the hematology of sows allows timely measures to prevent anemia, which inevitably occurs, since the targeted screening and selection of industrial  breeds  are  aimed  at  multiple births,  which  increases  the  risks of  anemia during pregnancy and suckling period. With periodic and constant monitoring, it is possible to deduce individual reference intervals of  hematological  indicators  for  a  particular animal and control the response to compensatory measures that directly affects the yield of viable piglets and their survival rate. The purpose of this study was to study the number  of  red  blood  cells,  hemoglobin  level, hematocrit,  average  volume  of  red  blood cells  and  erythrocyte  indices  depending  on the production cycle of the sow. The groups were formed from sows on the 80th day of pregnancy  (group  1,  n=5),  after  farrowing (group  2,  n=5)  and  before  weaning  piglets (group  3, n=5). The  Vet ABCTM analyzer (Horiba Medical Poland) was used. Counting of reticulocytes by “supravital staining” with a solution of “brilliant cresyl blue”. Statistical  processing  in  the  Microsoft  Excel  program (Data Analysis package), evaluation of the  reliability  of  differences  based  on  the Mann—Whitney U criterion. As a result, it was  found  that  the  average  volume  of  red blood cells increases with a decrease in their number  and  hemoglobin  concentration, which is quite natural and indicates a regenerative response with the appearance of reticulocytes in the blood. The correlation coefficient between erythrocytes and the average  volume  of  erythrocytes  was  r=-0.53 (r2=0.28, p=0.01), between the average volume  of  erythrocytes  and  reticulocytes  r=-0.50 (r2=0.25, p=0.05). There were no significant differences among the groups in reticulocytes and the average volume of erythrocytes. The dynamics and intensity of regeneration are moderate in all three groups.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>свиноматки</kwd><kwd>лабораторная  диагностика</kwd><kwd>гематология</kwd><kwd>эритроциты</kwd><kwd>ретикулоциты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>sows</kwd><kwd>laboratory diagnostics</kwd><kwd>hematology</kwd><kwd>erythrocytes</kwd><kwd>reticulocytes</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена при поддержке Российского научного  фонда,  грант №20-16-00032-П  (соглашение №20-16-00032-П  от 15.05.2023  г) https://rscf.ru/project/20-16-00032/.</funding-statement><funding-statement xml:lang="en">The studies were supported  by the Russian Science Foundation, grant  No.  20-16-00032-P  (agreement  No.  20-16-00032-P dated May 15, 2023) https://rscf.ru/project/20-16-00032/.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Евгина С.А., Савельев Л.И. 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