ivmМеждународный вестник ветеринарииInternational Journal of Veterinary Medicine2072-2419SpbGUVM Publishing House10.52419/issn2072-2419.2025.2.96ivm-1693Research ArticleФАРМАКОЛОГИЯ, ТОКСИКОЛОГИЯ, ФАРМАЦИЯPHARMACOLOGY, TOXICOLOGY, PHARMACYПрименение фитобиотика на основе эфирных масел для повышения иммунного статуса цыплят-бройлеровThe use of phytobiotics based on essential oils to enhance the immune status of broiler chickenshttps://orcid.org/0009-0007-0086-6487ЛыскоС. Б.LyskoS. B.

д-р ветеринар. наук, гл. науч. сотр. 

Doctor of Veterinary Sciences, Chief Researcher 

vet@subniip.ruhttps://orcid.org/0009-0006-3645-9923ГофманА. А.HoffmanA. A.

канд. ветеринар. наук, вед. науч. сотр. 

Candidate of Veterinary Sciences, Leading Researcher 

https://orcid.org/0009-0005-8607-1794ЗадорожнаяМ. В.ZadorozhnayaM. V.

канд. ветеринар. наук, вед. науч. сотр. 

Candidate of Veterinary Sciences, Leading Researcher 

https://orcid.org/0009-0001-8729-0850СунцоваО. А.SuntsovaO. A.

канд. ветеринар. наук, вед. науч. сотр. 

Candidate of Veterinary Sciences, Senior Researcher 

https://orcid.org/0000-0001-8351-2818ВласенкоВ. С.VlasenkoV. S.

д-р биол. наук, гл. науч. сотр. 

Doctor of Biological Sciences, Chief Researcher 

Федеральное государственное бюджетное научное учреждение «Омский аграрный научный центр»РоссияFederal State Budget Scientific Institution «Omsk Agrarian Scientific Center»Russian Federation2025010820250296104Copyright © Лыско С.Б., Гофман А.А., Задорожная М.В., Сунцова О.А., Власенко В.С., 20252025Лыско С.Б., Гофман А.А., Задорожная М.В., Сунцова О.А., Власенко В.С.Lysko S.B., Hoffman A.A., Zadorozhnaya M.V., Suntsova O.A., Vlasenko V.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vetjournal.spbguvm.ru/jour/article/view/1693

В условиях промышленного птицеводства на организм сельскохозяйственной птицы негативное влияние оказывают многочисленные стресс-факторы, что ведёт к развитию иммунодефицитных состояний, повышает восприимчивость к инфекционным заболеваниям, снижает сохранность и продуктивность поголовья. В связи с чем, для птицеводства весьма актуальным является применение иммунокоррегирующих препаратов. Целью исследования являлось изучение эффективности применения фитобиотика на основе комплекса эфирных масел корицы, гвоздики, розмарина лекарственного, тимьяна и кунжута индийского для повышения клеточного и гуморального иммунитет птицы. Исследования проводили на цыплятах-бройлерах кросса «Смена 9» из которых в суточном возрасте комплектовали контрольную и опытную группы по 70 голов в каждой. Цыплята опытной группы получали фитопрепарат в дозе 0,2 мл/л воды с 1-го по 7-й день выращивания и 0,3 мл/л воды – с 8-го по 38-й день. В возрасте 9 дней проведена вакцинация птицы против вируса Ньюкаслской болезни. На основании результатов исследований установлено, что использование препарат на основе эфирных масел повышает адаптационные способности цыплят-бройлеров после вакцинации, снижает негативные последствия стресс-факторов (биологический, технологический) на организм, активизирует клеточный и гуморальный иммунитет. Большее влияние фитобиотик оказал на показатели клеточного иммунитета, о чём свидетельствовало повышение содержания лимфоцитов в 1,8 раза, Т-лимфоцитов – в 2,9 раза, В-лимфоцитов – в 1,7 раза, катионных белков – на 40,3-85,6%, уровня спонтанной и стимулированной НСТ-активности нейтрофилов – на 37,3-49,0%. Применение препарата способствовало повышению среднего титра поствакцинальных антител к вирусу Ньюкаслской болезни на 0,5-0,8 log2.

In the conditions of industrial poultry farming, the body of poultry is negatively affected by numerous stress factors, which leads to the development of immunodeficiency conditions, increases susceptibility to infectious diseases, reduces the safety and productivity of livestock. In this regard, the use of immunocorrecting drugs is very relevant for poultry farming. The aim of the study was to study the effectiveness of using a phytobiotic based on a complex of essential oils of cinnamon, cloves, rosemary, thyme and sesame seeds to enhance cellular and humoral immunity of poultry. The studies were carried out on broiler chickens of the «Smena 9» cross, of which control and experimental groups of 70 heads each were completed at the age of one day. The chickens of the experimental group received phytopreparation in a dose of 0,2 ml/l of water from the 1st to the 7th day of cultivation and 0,3 ml/l of water from the 8th to the 38th day. At the age of 9 days, poultry was vaccinated against the Newcastle disease virus. Based on the research results, it has been established that the use of a preparation based on essential oils increases the adaptive abilities of broiler chickens after vaccination, reduces the negative effects of stress factors (biological, technological) on the body, activates cellular and humoral immunity. The phytobiotic had a greater effect on cellular immunity, as evidenced by an increase in the content of lymphocytes by 1,8 times, Tlymphocytes – by 2,9 times, B-lymphocytes by – 1,7 times, cationic proteins – by 40,3- 85,6%, and the level of spontaneous and stimulated HCT activity of neutrophils by 37,3-49,0%. The use of the drug contributed to an increase in the average titer of postvaccination antibodies to the Newcastle disease virus by 0,5-0,8 log2.

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The authors declare that there are no conflicts of interest present.