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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ivm</journal-id><journal-title-group><journal-title xml:lang="ru">Международный вестник ветеринарии</journal-title><trans-title-group xml:lang="en"><trans-title>International Journal of Veterinary Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-2419</issn><publisher><publisher-name>SpbGUVM Publishing House</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52419/issn2072-2419.2025.3.497</article-id><article-id custom-type="elpub" pub-id-type="custom">ivm-1844</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АКУШЕРСТВО, ГИНЕКОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OBSTETRICS, GYNECOLOGY</subject></subj-group></article-categories><title-group><article-title>Обмен веществ у лактирующих коров при субклиническом мастите</article-title><trans-title-group xml:lang="en"><trans-title>Metabolism in lactating cows with subclinical mastitis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4553-7189</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ирхина</surname><given-names>В. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Irkhina</surname><given-names>V. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>науч. сотр. отд. животноводства и птицеводства</p></bio><bio xml:lang="en"><p>research fellow, Department of Animal Husbandry and Poultry Farming </p></bio><email xlink:type="simple">irkhin83@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2996-0991</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Остякова</surname><given-names>М. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Ostyakova</surname><given-names>M. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р биол. наук, доц., директор </p></bio><bio xml:lang="en"><p>Dr. Sci. (Biol.), Associate Professor, Director </p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Дальневосточный зональный научно-исследовательский ветеринарный институт»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Far Eastern Zonal Research Veterinary Institute</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>07</day><month>01</month><year>2026</year></pub-date><volume>0</volume><issue>3</issue><fpage>497</fpage><lpage>503</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ирхина В.К., Остякова М.Е., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Ирхина В.К., Остякова М.Е.</copyright-holder><copyright-holder xml:lang="en">Irkhina V.K., Ostyakova M.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vetjournal.spbguvm.ru/jour/article/view/1844">https://vetjournal.spbguvm.ru/jour/article/view/1844</self-uri><abstract><p>Одним из ключевых факторов, замедляющих рост молочной продуктивности и ухудшающих санитарные показатели молока, произведенного в хозяйствах, являются маститы. Эти заболевания могут проявляться в различные периоды жизни коров, включая лактацию, запуск и сухостой, однако, наиболее часто они возникают именно в лактационный период, когда молочная железа подвергается значительным нагрузкам. Исследования были направлены на анализ проявления маститов у молочных коров в условиях Амурской области. Объект исследования- высокопродуктивные коровы голштинской породы, средней живой массой 600±50 кг. С целью проведения комплексного анализа метаболических процессов у лактирующих коров были сформированы две группы, по десять животных в каждой. Первая группа состояла из коров с подтвержденным субклиническим маститом, в то время как вторая группа включала клинически здоровых особей. Диагноз субклинический мастит ставили путем использования экспресс-диагностикума Кенотест. В ходе исследования был проведен анализ биохимических показателей сыворотки крови коров с субклинической формой мастита. У коров первой группы с субклиническим маститом были повышены значения билирубина на 45,5% (р&lt;0,05), холестерина на 38,7% (р&gt;&lt;0,05). Со стороны минерального обмена отмечали повышение фосфора на 37,5% (р&gt;&lt;0,001) и пониженный уровень кальция на 13,0% (р&gt;&lt;0,05). Белковый обмен у коров с субклиническим маститом характеризовался более низким уровнем альбуминов (на 18,1%, р&gt;&lt;0,001). В сыворотке крови на фотометре StatFax 1904+R с биохимическими реактивами «Витал» измеряли уровни показателей крови. Для статистической обработки использовали Microsoft Excel, вычисляя среднее арифметическое (М), ошибку среднего (m). &gt; &lt; 0,05), холестерина на 38,7% (р &lt; 0,05). Со стороны минерального обмена отмечали повышение фосфора на 37,5% (р &lt; 0,001) и пониженный уровень кальция на 13,0% (р&lt;0,05). Белковый обмен у коров с субклиническим маститом характеризовался более низким уровнем альбуминов (на 18,1%, р&gt; &lt; 0,001). В сыворотке крови на фотометре StatFax 1904+R с биохимическими реактивами «Витал» измеряли уровни показателей крови. Для статистической обработки использовали Microsoft Excel, вычисляя среднее арифметическое (М), ошибку среднего (m).</p></abstract><trans-abstract xml:lang="en"><p>Mastitis is one of the key factors slowing down the growth of milk productivity and worsening the sanitary indicators of milk produced on farms. These diseases can manifest themselves in different periods of the cows' life, including lactation, start-up and dry period, however, they most often occur during the lactation period, when the mammary gland is subjected to significant loads. The research was aimed at analyzing the manifestation of mastitis in dairy cows in the Amur region. The object of the study is highly productive Holstein cows with an average live weight of 600±50 kg. In order to conduct a comprehensive analysis of metabolic processes in lactating cows, two groups of ten animals each were formed. The first group consisted of cows with confirmed subclinical mastitis, while the second group included clinically healthy individuals. The diagnosis of subclinical mastitis was made using the Kenotest express diagnostic kit. The study included an analysis of biochemical parameters of the blood serum of cows with subclinical mastitis. In the cows of the first group with subclinical mastitis, the bilirubin values were increased by 45.5% (p&lt;0.05), cholesterol by 38.7% (p&gt;&lt;0.05). In terms of mineral metabolism, an increase in phosphorus by 37.5% (p&gt;&lt;0.001) and a decreased calcium level by 13.0% (p&gt;&lt;0.05) were noted. Protein metabolism in cows with subclinical mastitis was characterized by a lower level of albumin (by 18.1%, p&gt;&lt;0.001). Blood serum levels were measured using a StatFax 1904+R photometer with Vital biochemical reagents. Microsoft Excel was used for statistical processing, calculating the arithmetic mean (M), and the error of the mean (m). &gt; &lt; 0.05), cholesterol by 38.7% (p &lt; 0.05). In terms of mineral metabolism, an increase in phosphorus by 37.5% (p &lt; 0.001) and a decreased calcium level by 13.0% (p &lt; 0.05) were noted. Protein metabolism in cows with subclinical mastitis was characterized by a lower level of albumin (by 18.1%, p &lt; 0.001). Blood serum levels were measured using a StatFax 1904+R photometer with Vital biochemical reagents. Microsoft Excel was used for statistical processing, calculating the arithmetic mean (M), and the error of the mean (m).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Амурская область</kwd><kwd>субклинический мастит</kwd><kwd>лактирующие коровы</kwd><kwd>кровь</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Amur Region</kwd><kwd>subclinical mastitis</kwd><kwd>lactating cows</kwd><kwd>blood</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Позовникова, М. В.Идентификация и анализ значимых локусов генома, ассоциированных с устойчивостью к маститу у айрширских коров методом GWAS / М. В. Позовникова, О. В. Тулинова, О. К. Васильева, Ю. С. Щербаков // Животноводство и кормопроизводство. – 2024. – Т. 107, № 4. – С. 68-82. – DOI 10.33284/2658-3135-107-4-68. Режим доступа: https://www.elibrary.ru/item.asp?id=8025660</mixed-citation><mixed-citation xml:lang="en">Pozovnikova, M. 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