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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ivm</journal-id><journal-title-group><journal-title xml:lang="ru">Международный вестник ветеринарии</journal-title><trans-title-group xml:lang="en"><trans-title>International Journal of Veterinary Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-2419</issn><publisher><publisher-name>SpbGUVM Publishing House</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52419/issn2072-2419.2025.4.317</article-id><article-id custom-type="elpub" pub-id-type="custom">ivm-1898</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>БИОХИМИЯ, МОРФОЛОГИЯ, ФИЗИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BIOCHEMISTRY, ANATOMY, PHYSIOLOGY</subject></subj-group></article-categories><title-group><article-title>Физиологические механизмы усиления остеогенеза у уток под воздействием наночастиц бентонита в период эмбриогенеза</article-title><trans-title-group xml:lang="en"><trans-title>Physiological mechanisms of enhanced osteogenesis of ducks under the influence of bentonite nanoparticles during embryogenesis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4908-4316</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тодороски</surname><given-names>К.</given-names></name><name name-style="western" xml:lang="en"><surname>Todoroski</surname><given-names>K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. биол. наук, доц. департамента физической культуры, спорта и медиакоммуникаций </p></bio><bio xml:lang="en"><p>PhD in Biological Sciences, Associate Professor of the Department of Physical Education, Sports and Media Communications</p></bio><email xlink:type="simple">kiriltodoroski96@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5526-2214</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ежкова</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Ezhkova</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р биол. наук, проф., зав. каф. физиологии и патологической физиологии</p></bio><bio xml:lang="en"><p>Doctor of Biological Sciences, Professor, Head of the Department of Physiology and Pathological Physiology</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6476-6054</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ежков</surname><given-names>В. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Ezhkov</surname><given-names>V. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р ветеринар. наук, проф. каф. физиологии и патологической физиологии </p></bio><bio xml:lang="en"><p>Doctor of Veterinary Sciences, Professor of the Department of Physiology and Pathological Physiology</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский городской педагогический университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow City University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Казанский государственный аграрный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kazan State Agrarian University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>317</fpage><lpage>324</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тодороски К., Ежкова А.М., Ежков В.О., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Тодороски К., Ежкова А.М., Ежков В.О.</copyright-holder><copyright-holder xml:lang="en">Todoroski K., Ezhkova A.M., Ezhkov V.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vetjournal.spbguvm.ru/jour/article/view/1898">https://vetjournal.spbguvm.ru/jour/article/view/1898</self-uri><abstract><p>В работе исследовано влияние наносуспензии модифицированного бентонита Тарн-Варского месторождения (Республика Татарстан) на минеральную плотность костной ткани уток при обработке инкубационных яиц в период эмбриогенеза. Эксперимент проведён на 60 инкубационных яйцах пекинской породы, равномерно распределённых на контрольную и опытную группы; обработку 20% наносуспензией бентонита выполняли на 7-й и 13-й сутки инкубации, что соответствует критическим стадиям закладки и минерализации костной ткани [<xref ref-type="bibr" rid="cit1">1</xref>]. После вылупления в каждой группе сформировали по 20 утят, для рентгенологического анализа в возрасте 3–6 недель отбирали по 5 особей из каждой группы. Рентгенограммы выполняли в вентродорсальной проекции с последующим цифровым анализом яркости в 256 градациях серого и статистической обработкой данных (t-критерий Стьюдента, p&lt;0,05). Результаты показывают статистически значимое повышение минеральной плотности костной ткани у утят опытной группы во всех изученных анатомических зонах: тела шейного позвонка, диафизов и эпифизов плечевой, локтевой и бедренной костей. Наиболее выраженный эффект отмечен в дистальном эпифизе бедренной кости (увеличение до ~13–28% в разные возрастные интервалы, p&lt;0,01) и в средней части диафиза бедра. Положительная динамика сохранялась на протяжении всего наблюдаемого периода (3–6 недель), что свидетельствует о длительном остеотропном действии нанобентонита. Полученные данные подтверждают высокую биодоступность и потенциал наноформ бентонита для стимуляции остеогенеза и повышения прочности скелета у водоплавающей птицы. Метод обработки инкубационных яиц наносуспензией бентонита можно рассматривать как перспективный подход для профилактики костных патологий и для дальнейших прикладных исследований в ветеринарной практике.</p></abstract><trans-abstract xml:lang="en"><p>This study investigates the effect of a nanosuspension of modified bentonite from the Tarn-Var deposit (Republic of Tatarstan, Russia) on the bone mineral density of ducks when applied to incubation eggs during embryogenesis. The experiment was conducted on 60 Pekin duck eggs, evenly divided into control and experimental groups. The eggs in the experimental group were treated with a 20% bentonite nanosuspension on the 7th and 13th days of incubation, corresponding to the critical stages of skeletal tissue formation and mineralization [<xref ref-type="bibr" rid="cit1">1</xref>]. After hatching, 20 ducklings were selected from each group, and radiological analysis was performed on five individuals per group at 3–6 weeks of age. Radiographs were taken in the ventrodorsal projection, followed by digital brightness analysis in 256 grayscale levels and statistical processing of the data (Student’s t-test, p&lt;0.05). The results demonstrated a statistically significant increase in bone mineral density in ducklings from the experimental group across all studied anatomical regions, including the cervical vertebral body and the diaphyses and epiphyses of the humerus, ulna, and femur. The most pronounced effect was observed in the distal epiphysis of the femur (an increase of approximately 13–28% across different age intervals, p&lt;0.01) and in the middiaphyseal region of the femur. The positive trend persisted throughout the observation period (3–6 weeks), indicating a prolonged osteotropic effect of the nanobentonite. The findings confirm the high bioavailability and potential of bentonite nanostructures for stimulating osteogenesis and improving skeletal strength in waterfowl. The method of treating incubation eggs with a bentonite nanosuspension can be considered a promising approach for preventing bone pathologies and for further applied research in veterinary and poultry science.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>бентонит</kwd><kwd>наночастицы</kwd><kwd>минеральная плотность костной ткани</kwd><kwd>утки</kwd><kwd>эмбриогенез</kwd><kwd>рентгенография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>bentonite</kwd><kwd>nanoparticles</kwd><kwd>bone mineral density</kwd><kwd>ducks</kwd><kwd>embryogenesis</kwd><kwd>radiography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Тодороски К. Мясная продуктивность и санитарно-гигиеническая оценка качества мяса уток при применении наноструктурного бентонита в кормлении и обработке инкубируемых яиц: дис. ... канд. биол. наук. Москва, 2023. 159 с. 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