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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ivm</journal-id><journal-title-group><journal-title xml:lang="ru">Международный вестник ветеринарии</journal-title><trans-title-group xml:lang="en"><trans-title>International Journal of Veterinary Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-2419</issn><publisher><publisher-name>SpbGUVM Publishing House</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52419/issn2072-2419.2025.4.377</article-id><article-id custom-type="elpub" pub-id-type="custom">ivm-1904</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>БИОХИМИЯ, МОРФОЛОГИЯ, ФИЗИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BIOCHEMISTRY, ANATOMY, PHYSIOLOGY</subject></subj-group></article-categories><title-group><article-title>Влияние количества лактаций коров на показатели биохимического и антиоксидантного профиля пастеризованного и непастреризованного молока</article-title><trans-title-group xml:lang="en"><trans-title>The effect of the number of lactation cows on the indicators biochemical and antioxidant profile of pasteurized and unpasteurized milk</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0257-1643</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Савина</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Savina</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>науч. сотр, гр. аналитической биохимии</p></bio><bio xml:lang="en"><p>Junior Researcher, of the Analytical Biochemistry Group</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6774-4288</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воронина</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Voronina</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. биол. наук, ст. науч. сотр. гр. аналитической биохимии</p></bio><bio xml:lang="en"><p>Candidate of Biological Sciences, Senior Researcher of the Analytical  Biochemistry Group</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1533-8680</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайцев</surname><given-names>С. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaitsev</surname><given-names>S. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р хим. наук, д-р биол. наук., вед. науч. сотр., руководитель группы аналитической биохимии</p></bio><bio xml:lang="en"><p>Doctor of Chemical Sciences, Doctor of Biological Sciences, Leading researcher, Head of the Analytical Biochemistry Group</p></bio><email xlink:type="simple">s.y.zaitsev@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное научное учреждение «Федеральный исследовательский центр животноводства - ВИЖ имени академика Л.К. Эрнста»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Research Center for Animal Husbandry named after Academy Member L.K. Ernst</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>377</fpage><lpage>383</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Савина А.А., Воронина О.А., Зайцев С.Ю., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Савина А.А., Воронина О.А., Зайцев С.Ю.</copyright-holder><copyright-holder xml:lang="en">Savina A.A., Voronina O.A., Zaitsev S.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vetjournal.spbguvm.ru/jour/article/view/1904">https://vetjournal.spbguvm.ru/jour/article/view/1904</self-uri><abstract><p>Молоко, как и продукты на его основе, богаты веществами, способными проявлять антиоксидантную активность и содержит несколько антиоксидантных систем. В данной работе рассмотрены аспекты изменения антиоксидантного статуса молока, проанализированного амперометрическим методом, в контексте изменения биохимического состава молока в разных лактациях. Обнаружены тенденции увеличения суммарной концентрации водорастворимых антиоксидантов (СКВА) при пастеризации молока. В первые три лактации у коров голштинской породы значение СКВА растет вместе с увеличением средних значений суточного удоя и количества соматических клеток (КСК) в молоке. Так СКВА не пастеризованного молока у коров первой лактации составило 15,85±0,66 мг/л, у коров второй лактации 17,03±2,18 мг/л, что на 6,9 % больше, у коров третьей лактации уже на 18,0% больше, чем у второй – 20,77±2,91 мг/л. Внутри групп так же наблюдается одинаковая тенденция увеличения СКВА при пастеризации молока: 1) на +27,3%; 2) на +27,9%; 3) на +21,65%. При этом сохраняется динамика роста СКВА пастеризованного молока и между группами: 1) 22,11±0,33 мг/л; 2) 23,63±2,21 мг/л; 3) 26,51±2,31 мг/л. Различия СКВА являются не только значимыми, но и достоверными, p≤0,05. Одновременно происходит незначительное снижение содержания жира и белка в молоке, при этом количество лактозы достоверно не изменяется. Для выводов о статистической достоверности межгрупповых различий были выполнены расчёты по U критерию Манна-Уитни. При условии, что Uэксп. ≤ Uэмп. (Uэмп. = 27 для n=10, при α=0,05; Uэмп. = 19 для n=10, при α=0,01).</p></abstract><trans-abstract xml:lang="en"><p>Milk and milk-based products are rich in substances capable of exhibiting antioxidant activity and contain several antioxidant systems. This paper examines aspects of changes in the antioxidant status of milk, analyzed by the amperometric method, in the context of changes in the biochemical composition of milk in different lactations. Tendencies for an increase in the total concentration of water-soluble antioxidants (TAWSA) during milk pasteurization were found. In the first three lactations, an increase in TAWSA in Holstein cows correlates with an increase in average daily milk yield and somatic cell count (SCC) in milk. Thus, the TAWSA of unpasteurized milk in cows of the first lactation was 15.85±0.66 mg/L, in cows of the second lactation 17.03±2.18 mg/L, which is 6.9% more, in cows of the third lactation it was already 18.0% more than in the second – 20.77±2.91 mg/L. Within the groups, the same tendency of increasing TAWSA during milk pasteurization is also observed: 1) by +27.3%; 2) by +27.9%; 3) by +21.65%. At the same time, the dynamics of growth of TAWSA of pasteurized milk is preserved between the groups: 1) 22.11±0.33 mg/L; 2) 23.63±2.21 mg/L; 3) 26.51±2.31 mg/L. The differences in TAWSA are not only significant, but also reliable, p≤0.05. At the same time, there is an insignificant decrease in the fat and protein content in milk, while the amount of lactose does not change reliably. To draw conclusions about the statistical significance of intergroup differences, calculations were performed using the MannWhitney U test. Under the condition that Uexp. ≤ Uem. (Uem. = 27 for n=10, with α=0.05; Uem. = 19 for n=10, with α=0.01).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>молоко коров</kwd><kwd>пастеризация молока</kwd><kwd>компонентный состав</kwd><kwd>антиоксидантная активность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cow's milk</kwd><kwd>milk pasteurization</kwd><kwd>component composition</kwd><kwd>antioxidant activity</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена при финансовой поддержке Министерства науки и высшего образования Российской Федерации в рамках выполнения государственного задания (регистрационный номер ЕГИСУ темы НИР FGGN-2024-0016).</funding-statement><funding-statement xml:lang="en">The work was carried out with the financial support of the Ministry of Science and Higher Education of the Russian Federation as part of the state assignment (EGISU registration number of the research topic FGGN-2024-0016).</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Pihlanto, A. 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