ivmМеждународный вестник ветеринарииInternational Journal of Veterinary Medicine2072-2419SpbGUVM Publishing House10.52419/issn2072-2419.2021.4.219ivm-798Research ArticleНЕЗАРАЗНЫЕ БОЛЕЗНИNON-COMMUNICABLE DISEASEСубклинический кетоз как фактор снижения репродуктивных показателей высокопродуктивных коровSubclinical ketosis as a factor reduction of reproductive indicators of high productive cowshttps://orcid.org/0000-0002-4698-3917ШиряевГ. В.ShiryaevG. V.

кандидат сельскохозяйственных наук, 

196601, г. Санкт-Петербург

PhD (Agr. Sci.) 

«Всероссийский научно-исследовательский институт генетики и разведения сельскохозяйственных животных – филиал ФГБНУ ФИЦ – ВИЖ имени академика Л. К. Эрнста»РоссияRussian Research Institute of Farm Animal Genetics and Breeding – Branch of the L.K. Ernst Federal Science Center for Animal HusbandryRussian Federation20213112202104219228Copyright © Ширяев Г.В., 20212021Ширяев Г.В.Shiryaev G.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vetjournal.spbguvm.ru/jour/article/view/798

Целю исследования- изучить влияния субклинического кетоза (СКК) на результативность искусственного осеменения высокопродуктивных молочных коров в послеотельный период. Исследуемые животные подобраны по принципу условных аналогов и разделены на 2 группы по 6 голов в каждой. 1 группа – животные с концентрацией в крови 3-гидроксибутарата˂ 1,0 ммоль/ л, 2 группа – животные с субклиническим кетозом с концентрацией 3-гидроксибутирата в крови в диапазоне 1,0-1,4 ммоль/л. Кровь у животных отобрана на 5-ый, 15-ый и 33-35- ый день после отела. В полученных образцах сыворотки крови определено содержание общего белка, альбумина, мочевины, глюкозы, холестерина, триглицеридов, кальция, фосфора, магния, креатинина, общего билирубина, активность ферментов трансаминаз и щелочной фосфатазы. Определена концентрация стероидных гормонов. Перед искусственным осеменением животных синхронизировали по схеме прессинх-овсинх. Большинство биохимических показателей крови не выходили за референсные значения. К моменту гормональной стимуляции половой охоты у коров с СКК фиксировали снижение 3-гидроксибутирата (˂ 1,0 ммоль/л) и повышение глюкозы (>3,0 ммоль/л). На 15-ый день после отела в группе с СКК происходило увеличение общего билирубина, холестерина, триглицеридов и магния (p˂ 0,01). На 15-ый день после отела в группе с СКК уровень тестостерона был выше на 13%. К моменту синхронизации уровень прогестерона в группе животных с СКК был ниже в сравнении с контрольной группой. В группе животных с СКК зафиксированы самые низкие репродуктивные показатели: индекс осеменения в группе с СКК был выше на 46%, сервис-период длительнее на 49 дней, межотельный период достоверно длительнее на 68 дней.

СКК, зафиксированный на 15-ый день после отела, способствует снижению репродуктивных показателей молочных высокопродуктивных коров. Нормализация концентрации 3-гидроксибутирата с субклинических до физиологически нормальных величин, и последующая гормональная синхронизация не снижают данного негативного влияния СКК.

Purpose

Purpose: The aim of the research is to study the effect of subclinical ketosis (SCK) on the effectiveness of artificial insemination of highly productive dairy cows in the postpartum period.

Materials and methods

Materials and methods. The studied animals were selected according to the principle of conditional analogs and were divided into 2 groups of 6 animals each. Group 1 - animals with a blood concentration of 3- hydroxybutyrate˂ 1.0 mmol / l, group 2 - animals with subclinical ketosis with a concentration of 3-hydroxybutyrate in the blood in the range of 1.0-1.4 mmol / l. Blood was collected from animals on the 5th, 15th and 33-35th days after calving. In the obtained blood serum samples, the content of total protein, albumin, urea, glucose, cholesterol, triglycerides, calcium, phosphorus, magnesium, creatinine, total bilirubin, the activity of transaminase enzymes and alkaline phosphatase was determined. The concentration of steroid hormones has been determined. Before artificial insemination, the animals were synchronized according to the pressinovsinh scheme.

Results

Results. Most of the biochemical blood parameters did not go beyond the reference values. By the time of hormonal stimulation of sexual heat in cows with SCK, a decrease in 3-hydroxybutyrate (˂ 1,0 mmol / l) and an increase in glucose (> 3.0 mmol / l) were recorded. On the 15th day after calving, in the group with SCK, there was an increase in total bilirubin, cholesterol, triglycerides, and magnesium (p˂ 0,01). On the 15th day after calving, testosterone levels were 13% higher in the SCK group. By the time of synchronization, the level of progesterone in the group of animals with SCK was lower in comparison with the control group. In the group of animals with SCK, the lowest reproductive indices were recorded: the insemination index in the group with SSC was higher by 46%, the service period was 49 days longer, the interbody period was significantly longer by 68 days (p˂ 0,05).

Conclusion

Conclusion. Subclinical ketosis, recorded on the 15th day after calving, helps to reduce the reproductive performance of high -yielding dairy cows. Normalization of the concentration of 3-hydroxybutyrate from subclinical to physiologically normal values, and subsequent hormonal synchronization do not reduce this negative effect of SCK.

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The authors declare that there are no conflicts of interest present.