Efficacy and effect on the functional state of dogs and cats of insecticidal drops of Neoteric protector 4 in Ctenocephalidosis

Due to the development of resistance in ectoparasites, it is advisable to use complex insectoacaricides for the treatment and prevention of arachnoentomoses in domestic animals, which not only reliably protect, but also do not cause intoxication. The aim of the research was to study the therapeutic efficacy and the effect on the functional state of dogs and cats of insecticidal drops Neoterika Protecto 4 in case of ctenocephalidosis. The spread of the invasion and experiments to determine the effectiveness and safety of the insecticide were carried out on cats and dogs of different social status. It was found that the use of insectoacaricide drops Neoterika Protecto 4 allows you to rid cats and dogs of fleas 48-72 hours after a single point application of the drug to the skin in the area between the shoulder blades. It is noted that the less the abundance of parasites on the animal, the faster the recovery. The residual insecticidal effect of the drug was at least thirty days. No deviations in the physiological state and behavior of animals were found. It was determined that flea infestation did not cause significant changes in the homeostasis of animals in terms of creatinine, urea, ALT and AST. In dogs of all ages studied, the de Ritis coefficient before the experiment was in the lower limits of the reference range, and three days after the use of the studied insecticide, the aminotransferase ratio approached the reference values. In cats, an increase in the de Ritis coefficient was recorded before the start of treatment, and high values were maintained immediately after the use of the studied insectoacaricide. In cats aged 1-7 years, a decrease in the aminotransferase ratio was observed, and in older cats, on the contrary, an increase in the de Ritis coefficient occurred. When using insectoacaricides, it is necessary to take into account the initial functional state of animals and, if necessary, include hepatoprotectors in the protocol of therapeutic measures to prevent the development of side effects and damage to the detoxification organs, especially in cats over seven years old.

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