Integral characteristics of the blood of the brood stock of common carp (Cyprinus carpio) with fatty liver
https://doi.org/10.52419/issn2072-2419.2025.4.384
Abstract
In modern veterinary ichthyopathology, hematological and biochemical blood studies are important diagnostic tools that allow assessment of the functional state of fish organisms under various pathologies. In this regard, the aim of this study was to evaluate the integral blood characteristics of common carp (Cyprinus carpio) broodstock with fatty liver dystrophy. The study used 20 specimens of common carp broodstock weighing 3900 g, raised at JSC "Fish Hatchery" in Voronezh Oblast. The aquatic organisms were divided into control and experimental groups of 10 specimens each. To model the pathology, the experimental group was kept in aquatic environment with added copper (II) sulfate at a concentration of 60 mg/L calculated as metal ion. Blood sampling was performed 56 hours after the start of the experiment from the caudal vein. Hematological parameters, blood plasma biochemical parameters, and oxidative stress markers were investigated using standardized methods. As a result, specimens in the experimental group showed pronounced hepatic dysfunction syndrome, manifested by hypoproteinemia with significant decrease in total protein by 17.7%, disproportional reduction of albumins by 22.3% and globulins by 14.4%. Cytolytic syndrome developed with a three-fold increase in ALT activity and a 1.4 -fold increase in AST. Hypercholesterolemia was observed with a 3.1-fold increase in cholesterol concentration, acute-phase response with an 11.5-fold increase in Creactive protein, and depletion of the antioxidant system. The hematological picture was characterized by development of microcytichypochromic anemia with a two-fold decrease in hemoglobin and compensatory erythrocytosis, leukocytosis, thrombocytopenia, and changes in the leukocyte formula with relative lymphopenia. The results confirm the high diagnostic value of hematological studies in fatty liver dystrophy in carp and may serve as a basis for early monitoring of broodstock.
About the Author
E. V. Semenova
All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy (ARVRIPP&T)
Russian Federation
Russian Federation
graduate student, Junior researcher, Laboratory of Innovative Recombinant Proteomics
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For citations:
Semenova E.V. Integral characteristics of the blood of the brood stock of common carp (Cyprinus carpio) with fatty liver. International Journal of Veterinary Medicine. 2025;(4):384-392. (In Russ.) https://doi.org/10.52419/issn2072-2419.2025.4.384
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