The effectiveness of “MASTINON” for mastitis in lactating cows

Abstract

The aim of the research is to explore the therapeutic efficacy of the remedy “Mastimn” for the treatment of catarrhal mastitis in cows. The remedy presents oxytetracycline, neomycin sulfate, bacitracin, prednisolone. Experimental research was carried out at the farm “ ZAO Michurina” of the Smolensk district of the Smolensk region and at the laboratory of the Smolensk separate division of “ FSC LC”, from march 06 to may 30, 2019 on lactating cows. The experiment included test (n=20) and control (n=18) groups of cows. The experimental group were administered intracisternally “Mastinon”. In the control group “Gamaret” was used. Diagnosis of mastitis was performed according to the" Manual on diagnosis, therapy and prevention of mastitis in cows " (2007), with the use of mast-test. Were determined the microbic-species composition of the microflora of secrets recieved; antimicrobial activity of the remedy “Mastinon” and “Gamaret”, using the method of disks. During the experiment, it was proved that the drug “Mastinon” has a high activity to the microflora, isolated from the udder secretions of cows with mastitis. So in relation to Str. agalactiae, the growth delay zone was 26 mm, in relation to Staph.aureus - 28 mm, E. Coli -23 mm. The drug “Gamaret” used in the farm, also had antimicrobial activity to the isolated microflora. But, apparently, cause of its regular use, there is a tendency to decrease in sensitivity, so for Str. agalactiae, the growth delay zone was 17 mm, Staph. aureus 19 mm, and E.Coli 22 mm. In 3 days, in experimental group - 19 heads recovered (95.0%), which is 23.6% more animals than from “Gamaret” (control). Experimental studies have shown high therapeutic efficiency of a new drug “Mastinon”, compared to constantly used in the household “Gamermom”.