Change of pigment exchange indexes in treatment of cows affected by chronic hepatosis

Abstract

The article describes the changes in pigment exchange rates in the treatment of cows suffering from hepatosis. Timely monitoring of metabolic status in highly productive dairy cows allows the fastest and most accurate diagnosis of liver pathology. The liver is involved in many kinds of metabolism, such as the exchange of lipids, proteins, carbohydrates, vitamins, pigments and many other substances. The use of combined treatment made it possible to reduce the concentration of total bilirubin in serum in the animals of the third experimental group by 36.4% by the 75th day (P <0.001), which is also the best result proving the greatest effectiveness of the combined use of these drugs. Cows of I and II experimental groups also had a significant decrease in the concentration of total bilirubin in the blood by 16.1% (P <0.01) and 13.9% (P <0.05), respectively, by 16.1% (P <0.01). Thus, when analyzing the clinical and biochemical data obtained in this study, it is determined that the combined administration of the drugs "Hepatodecept" and "Habivit-Se" allows to significantly reduce the concentration of total and bound bilirubin in the serum of patients with hepatosis of cows. This indicates that with the restoration of hepatocytes, a more complete capture of pigment metabolism products from the blood and their release in direct form from the hepatocyte into the bile ducts.