Resistance of lactobacilli to aflatoxin B1

Abstract

The study was conducted in the laboratory of mycotoxicology, where a secondary collection of lactobacillus, characterized by tolerance to mycotoxins and having a certain set of enzyme detoxification capabilities, was cultured on agar medium with a notoriously high content of aflatoxin В₁. In parallel, the property of destruction of aflatoxin В1 was fixed by the method of cumulative selection under the control of enzymes of oxidative degradation of metabolites. In the result of this work, it was possible to identify two strains of lactobacilli resistant to aflatoxin В₁. Further confirmation of morphological and economic useful properties of these strains will allow to create on their basis new specialized antitoxic preparations demanded for needs of practical animal farming. The experiments should be continued. The other bacterial species and other mycotoxins should be the subject of the further study as the xenobiotics potentially harmful for commercial poultry production. A promising direction of these study is the mode of application of these detoxifying agents: whether it should be a single-strain preparation active in a wide range of doses and types of toxicity, or for each situational level its own bacterial strain should potentially be "fixed" and combined into a complex drug. However, the prospectivity of bacterial agents for the destruction of mycotoxins in the intestine is now clear and doubtless since this method has several important advantages compared to the traditional approaches to the prevention of mycotoxicoses