Influence of hepaton on rectal temperature and duration of hexenal sleep

Abstract

This paper presents the results of clinical studies conducted on white rats using the hepatoprotector "Hepaton". To study the effect of the drug, the body temperature of animals was measured three times: before the experiment, 90 and 180 days after the introduction of the hepatoprotector. And also at the same time determined the duration of hexenal sleep. A TPEM-1 electric medical thermometer was used to measure rectal temperature, and a hexenal solution of 90 mg / kg with a solvent in the form of a 0.9% sodium chloride solution was used to determine the duration of hexenal sleep. Data on the measurement of rectal body temperature of rats showed the absence of significant differences in animals from the experimental and control groups. Body temperature throughout the experiment was within the physiological norm and ranged from 35.4 ° C to 36.7 ° C. Indicators on the duration of hexenal sleep indicated that the hepatoprotector significantly reduced sleep time 90 and 180 days after its use in the experimental group compared to the control group of rats, which indirectly indicates the activation of the liver detoxifying function under the influence of the hepaton dosage form.