Physiological and biochemical aspects of Chitosan application in veterinary medicine
https://doi.org/10.52419/issn2072-2419.2025.3.385
Abstract
Chitosan has a number of characteristics that make it relevant for use in veterinary medicine. It has antibacterial and antifungal properties, which makes it a promising tool for the treatment and prevention of infections in animals. This is especially important in conditions of increasing bacterial resistance to traditional antibiotics. Chitosan accelerates the wound healing process by stimulating fibroblast proliferation and angiogenesis. This makes it a valuable component for veterinary dressings and ointments. It is attractive that chitosan can stimulate the immune system of animals, which is associated with increased resistance to various infectious diseases. This polysaccharide can be used as an additive to animal feed, contributing to improved digestion and absorption of nutrients, as well as lowering cholesterol and triglycerides. According to a number of studies, chitosan and gels based on it are not toxic. Despite the extensive data on the numerous benefits of chitosan, there is insufficient data on potential side effects. There is also limited data on the combined use of chitosan with other drugs. The above indicates the need for further research.
Supporting agencies: The work was carried out within the framework of the Russian Science Foundation grant 25-26-00175 Molecular genetic mechanisms of immunity formation and the rumen microbiome in young cattle under the influence of chitosan. (https://grant.rscf.ru/site/user/bids?role=master).
About the Authors
A. B. Balykina
St. Petersburg State University of Veterinary Medicine
Russian Federation
Russian Federation
PhD of Veterinary Sciences, Assoc. Prof.
L. Yu. Karpenko
St. Petersburg State University of Veterinary Medicine
Russian Federation
Russian Federation
D.Biol.sc. Professor
M. V. Kiyanchuk
St. Petersburg State University of Veterinary Medicine
Russian Federation
Russian Federation
assistant of the Department of Biochemistry and Physiology
I. N. Nikonov
St. Petersburg State University of Veterinary Medicine
Russian Federation
Russian Federation
Cand.biol.sc.
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Review
For citations:
Balykina A.B., Karpenko L.Yu., Kiyanchuk M.V., Nikonov I.N. Physiological and biochemical aspects of Chitosan application in veterinary medicine. International Journal of Veterinary Medicine. 2025;(3):385-396. (In Russ.) https://doi.org/10.52419/issn2072-2419.2025.3.385
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