Fusogel is an effective remedy for the treatment of cows with hoof diseases
https://doi.org/10.52419/issn2072-2419.2025.3.511
Abstract
In recent decades, hoof diseases have continued to cause significant damage to dairy cattle breeding. The most important condition for increasing the productivity and longevity of cows in dairy cattle breeding is effective prevention of hoof diseases and their timely treatment at the very beginning of the disease. A new drug, Fuzogel, has been developed at the Federal Center for Traumatology and Radiology of the Russian Academy of Sciences. The aim of the work was to evaluate the effectiveness of the new import-substituting drug, Fuzogel, in the form of a gel based on the active substances of copper and zinc metal complex compounds, in hoof diseases in cows. The gel form creates a mechanical barrier that prevents the development of infection by reducing the adhesion of vegetative and spore forms of bacteria and fungi to the tissues of the fingers and hooves. Tests of the effectiveness of this product in infectious and non -infectious hoof diseases in cows conducted in two agricultural enterprises indicate its high antimicrobial and anti-inflammatory activity in the initial and moderate severity of hoof lesions, rapid relief of the inflammatory response in such clinical manifestations of diseases as: digital dermatitis, ulcer of the pulp, coronary band, interdigital space vault, pododermatitis. "Fusogel", which does not contain antibiotics, can be used without restrictions on dairy cattle, which allows obtaining high-quality products (milk, meat, offal). After the use of "Fusogel" in cows with mild and moderate severity of the disease, previously detected vegetative forms of bacteria and microscopic fungi were completely absent, which positively affected the regenerative processes and restoration of hoof functions in cows. The high effectiveness of the drug allows its wide implementation in the system of measures to combat hoof diseases in cattle.
About the Authors
D. A. KhuzinRussian Federation
Doctor of Biological Sciences, Associate Professor, Chief Researcher
E. Yu. Tarasova
Russian Federation
Candidate of Biological Sciences, Head of the Laboratory of Veterinary Sanitation
F. Z. Baimukhametov
Russian Federation
Candidate of chemistry sciences, researcher
G. N. Spiridonov
Russian Federation
Doctor of Biological Sciences, Head of the Laboratory of Bacterial Pathologies of Animals
P. V. Bykova
Russian Federation
Junior Researcher
S. A. Yusupov
Russian Federation
Candidate of Veterinary Sciences, Senior Researcher
R. M. Potekhina
Russian Federation
Candidate of Biological Sciences, Leading Researcher
G. R. Lukina
Russian Federation
Junior Researcher
References
1. Analysis of the epizootic situation for infectious diseases of fingers and hooves of cattle in certain regions of the Russian Federation / D. A. Khuzin, E. Yu. Tarasova, R. M. Potekhina [et al.] // International Bulletin of Veterinary Medicine. - 2024. - No. 1. - P. 33-40. - DOI 10.52419/issn2072-2419.2024.1.33. Access mode: https://elibrary.ru/item.asp?id=67347103 (In Russ.)
2. Korochkin, R. B. Necrobacteriosis of the extremities - a problem of modern cattle breeding / R. B. Korochkin // Our agriculture. - 2022. - No. 16 (288). - P. 42-45. Access mode: https://www.elibrary.ru/item.asp?id=49478554 (In Russ.)
3. Results of bacteriological examination of swabs from purulent-necrotic lesions of hooves in cattle / D. N. Nadezhdin, E. M. Maryin, O. N. Maryina [et al.] // Bulletin of the Orenburg State Agrarian University. - 2025. - No. 1 (111). - P. 151-158. Access mode: https://www.elibrary.ru/item.asp?id=80372393
4. Improving lameness detection in cows: A machine learning algorithm application / E. Dervić, C. Matzhold, C. Egger-Danner [et al.] // J. Dairy Sci. – 2024. – Vol. 107. – Р. 11550-11562. – DOI 10.3168/jds.2024- 24730. Access mode: https:// www.sciencedirect.com/science/article/pii/S0022030224011457
5. Associations of lameness with milk composition, fatty acid profile, and milk coagulation properties in mid-lactation highyielding Holstein cows / M. Kass, P. Karis, R. Leming [et al.] // International Dairy Journal. – 2024. – № 153. –105908. – DOI 10.1016/j.idairyj.2024.105908. Access mode: https://www.researchgate.net/publication/322030771_Cow_milk_coagulation_Process_description_variation_factors_and_evaluation_methodologies_a_review
6. Combined pathologies of the distal limbs in cows of dairy productivity / S. V. Pozyabin, E. N. Borkhunova, V. V. Belogurov [et al.] // International Bulletin of Veterinary Medicine. - 2024. - No. 2. - P. 362-371. - DOI 10.52419/issn2072-2419.2024.2.362. Access mode: https://elibrary.ru/item.asp?id=68597317
7. Towards potential antifungal agents: synthesis, supramolecular self-assembly and in vitro activity of azole mono- , sesqui- and diterpenoids / A. Akhmedov, R. Gamirov, Yu. Panina [et al.] // Organic & Biomolecular Chemistry. – 2023. – Vol. 21, No. 23. – P. 4863-4873. Access mode: https://elibrary.ru/item.asp?id=53959743
8. Grimm, K. Investigation on the effectiveness of a new hoof care product to sustainably reduce and prevent digital dermatitis in dairy cow herds / K. Grimm, A. Fiedler, C. Kröger // J. Dairy Sci. – 2025. – № 108(2). – Р. 1869-1881. – DOI 10.3168/jds.2024-25134.
9. Evaluation of ultrastructural changes in Fusobacterium necrophorum under the influence of agents used for group prevention of diseases of the distal limbs of ungulates / K. V. Perfilova, G. S. Kashevarov, V. R. Saitov [et al.] // Bulletin of the Kursk State Agricultural Academy. - 2023. - No. 1. - P. 153-158. Access mode: https://elibrary.ru/item.asp? id=50745274 (In Russ.)
10. Nekhaychik, F. M. Corrosion activity and foaming ability of a new disinfectant / F. M. Nekhaychik, D. N. Mingaleev // The Veterinarian. – 2022. – No. 1. – P. 26-30. – DOI 10.33632/1998-698X.2021-1-26-30. Access mode: https://www.elibrary.ru/item.asp?id=48060758 (In Russ.)
11. Study of antimicrobial and fungicidal activity of a disinfectant for livestock premises in the presence of animals / D. A. Khuzin, T. A. Shamilova, A. M. Tremasova [et al.] // The Veterinarian. – 2023. - No. 4. - P. 20-26. - DOI 10.33632/1998- 698X_2023_4_20. Access mode: https://www.elibrary.ru/item.asp?id=54307926 (In Russ.)
12. The role of saprophytic and opportunistic microorganisms in the occurrence and spread of opportunistic infections of cattle / D. A. Khuzin, S. A. Yusupov, A. I. Eroshin [et al.] // Scientific notes of the Kazan State Academy of Veterinary Medicine named after. N.E. Bauman. – 2022. – Vol. 252, No. 4. – P. 267-272. – DOI 10.31588/2413_4201_1883_4_252_267. Access mode: https://www.elibrary.ru/item.asp?id=49843434 (In Russ.)
13. Khudoerova, F. A. The problem of hoof diseases in highly productive dairy cows and preventive measures / F. A. Khudoerova, H. A. Khamdamov // Theory and practice of modern science: a collection of articles from the III International scientific and practical conference, Penza, October 20, 2020. - Penza: "Science and Education", 2020. - P. 139- 142. Access mode: https://www.elibrary.ru/item.asp?id=44081474 (In Russ.)
Review
For citations:
Khuzin D.A., Tarasova E.Yu., Baimukhametov F.Z., Spiridonov G.N., Bykova P.V., Yusupov S.A., Potekhina R.M., Lukina G.R. Fusogel is an effective remedy for the treatment of cows with hoof diseases. International Journal of Veterinary Medicine. 2025;(3):511-519. (In Russ.) https://doi.org/10.52419/issn2072-2419.2025.3.511
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