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Medication “Argovit - spray 3 ” proved to have an action against wound infection causative agents

Abstract

The wound fever is one of the most widespread complications at therapy of wounds of various etiology. In most cases, an etiological factor of development of this pathology is contamination of an operational wound by representatives of an opportunistic microflora. Recently for prophylaxis and therapy of a wound fever, the set of the medicines including containing in the structure silver in various aggregate state is offered. In LLC SPC Vektor-Vita means was developed for treatment of wounds of various etiology "Argovit spray-3". Data on studying of antibacterial activity of this medicine containing cluster silver, polyethylene glycol, and a dimethylsulfoxide, intended for sanitation of a wound surface of skin are provided in article. As a result of the conducted researches it was established that "Argovit spray-3" has the expressed antibacterial activity concerning the activators of a wound fever which are falling into to the sorts St. albus, Str. pyogenes, E.coli, Ps.aeruginosae. The treat-ment-and-prophylactic effectiveness of medicine was confirmed in experience on laboratory animals. To guinea pigs gave scrappy wounds and the surface burns. Use of medicine "Argovit-spray-3" at therapy of scrappy wounds promoted acceleration and quality of an epitalization; and at therapy of burns - prevented development of complications in the form of purulent inflammation that positively affected regeneration and terms of an adhesion. Clinical tests of medicine carried out on cats to whom they gave cut wounds. Watched a clinical condition of animals within 14 days. Use of medicine "Argovit-spray-3" during the entire period of an adhesion interfered with development of purulent complications and inflammatory phenomena in the field of drawing cut wounds.

About the Authors

V. Yu. Koptev
Siberian Institute of experimental veterinary science of Siberia and the Far East Siberian Federal scientific center of agrobiotechnology of the Russian Academy of Sciences
Russian Federation


S. A. Bolyahina
Siberian Institute of experimental veterinary science of Siberia and the Far East Siberian Federal scientific center of agrobiotechnology of the Russian Academy of Sciences
Russian Federation


G. F. Nasartdinova
Siberian Institute of experimental veterinary science of Siberia and the Far East Siberian Federal scientific center of agrobiotechnology of the Russian Academy of Sciences
Russian Federation


V. A. Burmistrov
LLC SPC «Vector-Vita»
Russian Federation


References

1. Антонен Е.Ю. Хирургические болезни собак стафилококковой этиологии // Международный вестник ветеринарии. - 2008. - № 4. № 2. С.3-7.

2. Гадзаонов, Сослан Георгиевич Лечение инфицированных ран у собак и крупного рогатого скота с использованием препаратов чистотела на фоне физиотерапии: автореф. дис.. канд. вет. наук. - Владикавказ. - 2009. - 23 с.

3. Козлов Е.М. Травматизм и лечение повреждений у кошек и собак / Е.М. Козлов // Проблемы адаптации сельскохозяйственных животных: материалы научно-практической конференции, посвященной 65-летию Иркутской ИИВС. Новосибирск, 1997. - С. 196-197.

4. Глущенко, Василий Вячеславович Микробиоценоз инфицированных ран и динамика иммунобиологических показателей у собак при лечении перкутаном: автореф. Дис.. канд. вет наук. - Барнаул. - 2007. - 19 с.

5. Гнетнев А.М., Бабушкина И.В., Рузанов В.И., Родионов П.П., Бурмистров В.А. Местное лечение гнойных осложнений препаратами серебра в травматологии // Применение препаратов серебра в медицине (по материалам научно-практической конференции «Новые химические системы и процессы в медицине» Новосибирск, 21-22 декабря 2001 г.) - 2003. - С.34-37.

6. Фисенков Н.Н., Войтенко В.Д. Способ снижения нагноения ран//Международный вестник ветеринарии. - 2014. - № 4 - С. 32-37.

7. Sawosz E.Et. Al. // Arch. Anim Nutr. - 2007 / -Vol. 61, N.6. - P. 444-451.

8. Silver, Our Mightiest Germ Fighter. - Science Digest, March 1978.


Review

For citations:


Koptev V.Yu., Bolyahina S.A., Nasartdinova G.F., Burmistrov V.A. Medication “Argovit - spray 3 ” proved to have an action against wound infection causative agents. International Journal of Veterinary Medicine. 2018;(2):49-53. (In Russ.)

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ISSN 2072-2419 (Print)