Hyaluronic acid as a means to correct entropion in animals

Abstract

Entropion, or inversion of the edge of the eyelid, is a frequent multifactorial disease in which the ciliated edge of the eyelid is wrapped inside, which leads to permanent corneal trauma and eye irritation. Currently, subcutaneous fillers based on hyaluronic acid are used to correct entropion due to the fact that it does not have organ- and speciesspecificity and, therefore, carries a minimal risk of allergic reactions. The advantage of subcutaneous fillers based on HA is that the injection can be reversed with the development of complications with the help of drugs based on hyaluronidase. The assessment was carried out by the amount of periocular moistening, alopecia and/or hyperemia of the eyelids with manual rotation of the eyelids outward during the examination. All patients underwent a complete ophthalmological examination with a slit lamp and indirect ophthalmoscopy, a Schirmer test and intraocular pressure. The injection methods used included linear threading, a series of single-point injections, or a combination of them. The criteria for evaluating the effectiveness of the use of hyaluronic acid as a means for correcting entropion in animals were local reactions to skin filler, inflammatory processes in the eye area associated with a relapse of entropion, as well as the duration of the period before repeated administration of the drug. The technique of subcutaneous injection of the GC filler is a simple, reliable, effective, safe, prolonged procedure that requires a minimum amount of time, which allows you to immediately alleviate the patient's condition from mild to moderate severity as a result of entropion in cats and dogs. This procedure is especially preferable for age-related patients and patients with high anesthetic risk.