To study the anabolic aspects of lactation in cows in connection with the intensity of ketogenesis in the new body period
https://doi.org/10.52419/issn2072-2419.2023.4.447
Abstract
The article discusses the results of a study of the milk productivity of cows in connection with the content of beta-hydroxybutyric acid in the blood during the new calving period. The studies were carried out on highly productive full-aged cows of the second and third lactation. The animals were divided into three groups according to the content of beta-hydroxybutyrate - up to 1.0 mmol/l; from 1.0 to 2.0 mmol/l and over 2.0 mmol/l. It has been established that an increase in the content of ketones in the blood is associated with hypoglycemia. Cows with increased levels of beta-hydroxybutyric acid at the beginning of lactation showed higher daily milk yields over a five-month period of observation. In the fourth and fifth months of lactation, the milk yield of these cows was higher than in groups 1 and 2 by 14.6-15.8% and 18.5-20.1%, respectively. In addition, the total yield of fat in this group is greater than in the first and second - by 12.8% and 10.7%, protein - by 9.7% and 11.2%, and lactose - by 8.5% and 13.5%, respectively. A calculation indicator was proposed - the lactation anabolism index, which is calculated using daily milk yield, mass fraction of milk protein and urea concentration. An increase in this index indicates the activation of anabolic reactions, a decrease indicates a surge in catabolic processes. An increase in the lactation anabolism index was found in cows of the third group at 4-5 months of lactation with a significant increase of 44.8-45.8% in comparison with groups 1 and 2. A high metabolic potential for further productive lactation was established in cows that had increased concentration of beta-hydroxybutyric acid in the new calving period.
About the Author
S. V. VasilevaRussian Federation
Candidate of Veteriary Sciences, Associate Professor of the Department of Biochemistry and Physiology
References
1. Konopatov, Yu. V. Biochemistry of animals / Yu. V. Konopatov, S. V. Vasilyeva. – 1st, New. – St. Petersburg: Lan Publishing House, 2015. – 176 p. – ISBN 978-5-8114-1823-7. URL: https://www.elibrary.ru/item.asp?id=25180633
2. Nikitina, A. A. Prevalence and diagnosis of subclinical ketosis in dairy cows during the transit period / A. A. Nikitina // Proceedings of the 75th anniversary international scientific conference of young scientists and students of St. Petersburg State University of Medicine, dedicated to the announced in 2021 by the President of the Russian Federation V.V. Putin, the year of science and technology, St. Petersburg, April 05–09, 2021. – St. Petersburg: St. Petersburg State University of Veterinary Medicine, 2021. – P. 159-161. URL: https://www.elibrary.ru/item.asp?id=45611037
3. Nikitina, A. A. Some indicators of the metabolism of cows during different periods of pregnancy and their impact on the clinical status / A. A. Nikitina // Veterinary Medicine. – 2023. – No. 10. – P. 41-44. – DOI 10.30896/0042-4846.2023.26.10.41-45. URL: https://www.elibrary.ru/item.asp?id=54651233
4. Blood parameters in cows with ketosis / S.P. Kovalev, P. S. Kiselenko, V. A. Trushkin, A. A. Nikitina // Current problems of innovative development of animal husbandry: International scientific and practical conference, Bryansk, May 30–31, 2019. – Bryansk: Bryansk State Agrarian University, 2019. – P. 86-89. URL: https://www.elibrary.ru/item.asp?id=38576828
5. Study of metabolic processes in cows with hyperbilirubinemia in the postpartum period / A. Nikitina, S. Vasileva, R. Vasilev [et al.] // FASEB Journal. – 2022. – Vol. 36, No. S1. – P. 3431. – DOI 10.1096/fasebj.2022.36.S1.R3431. URL: https://www.elibrary.ru/item.asp?id=48561184
6. Vasilieva, S. V. Influence of subclinical ketosis in cows on formation of colostral immunity in calves / S. V. Vasilieva, R. M. Vasiliev // Medical Immunology (Russia). – 2021. – Vol. 23. – No 4. – P. 981-986. – DOI 10.15789/1563-0625-IOS-2274. URL: https://www.elibrary.ru/item.asp?id=46687169
7. Changes in indicators of pigment metabolism in the treatment of cows with chronic hepatosis / A. A. Voinova, S. P. Kovalev, V. A. Trushkin, G. S. Nikitin // International Bulletin of Veterinary Medicine. – 2018. – No. 1. – P. 114-118. URL: https://www.elibrary.ru/item.asp?id=32703715
8. The influence of the hepatoprotector "Hepalan" on clinical and morphological blood parameters in first-calf cows with hepatosis / M. S. Golodiaeva, A. V. Prusakov, A. V. Yashin, V. D. Radnatarov // Bulletin of the Buryat State University - Gift Agricultural Academy named after. V.R. Filippova. – 2021. – No. 2(63). – pp. 136-140. – DOI 10.34655/bgsha.2021.63.2.019. URL: https://www.elibrary.ru/item.asp?id=46244259
9. Clinical study of an animal with a history of the disease / S. P. Kovalev, I. A. Nikulin, V. A. Trushkin [etc.]. – St. Petersburg: St. Petersburg State University of Veterinary Medicine, 2021. – 128 p. URL: https://www.elibrary.ru/item.asp?id=46441108
10. Golodiaeva, M. S. Influence of the hepatoprotector "Hepalan" on the structural organization of liver tissue of first-calf cows / M. S. Golodiaeva, A. V. Prusakov, A. V. Yashin // Issues of legal regulation - research in veterinary medicine. – 2021. – No. 2. – P. 114-117. – DOI 10.17238/issn2072-6023.2021.2.114. URL: https://www.elibrary.ru/item.asp?id=46196552
11. Study of metabolic processes in cows with hyperbilirubinemia in the postpartum period / A. Nikitina, S. Vasileva, R. Vasilev [et al.] // FASEB Journal. – 2022. – Vol. 36, No. S1. – P. 3431. – DOI 10.1096/fasebj.2022.36.S1.R3431. URL: https://www.elibrary.ru/item.asp?id=48561184
12. Baryshev, V. A. New methods for detoxification of heavy metals and mycotoxins in dairy cows / V. A. Baryshev, O. S. Popova, V. S. Ponamarev // Online Journal of Animal and Feed Research. – 2022. – Vol. 12, No. 2. – P. 81-88. – DOI 10.51227/ojafr.2022.11. URL: https://www.elibrary.ru/item.asp?id=48113521
13. Pharmacocorrection of hepatopathy of various etiologies in cattle: methodological recommendations / N. L. Andreeva, A. M. Lunegov, A. V. Yashin [etc.]. – St. Petersburg: St. Petersburg State University of Veterinary Medicine, 2020. – 19 p. URL: https://www.elibrary.ru/item.asp?id=44706307
14. The state of the antioxidant system in cows at different densities of radioactive contamination of the soil / P. S. Anipchenko, R. M. Vasilev, V. N. Gaponova [et al.] // FASEB Journal. – 2020. – Vol. 34, No. S1. – P. 05122. – DOI 10.1096/fasebj.2020.34.s1.05122. URL: https://www.elibrary.ru/item.asp?id=42887126
15. Morphological composition of blood in cows of the Aberdeen-Angus breed in the conditions of the Leningrad region / A. A. Voinova, S. P. Kovalev, G. S. Nikitin [etc.] // Issues of legal regulation in veterinary medicine. – 2017. – No. 4. – P. 142-144. URL: https://www.elibrary.ru/item.asp?id=30793493
Review
For citations:
Vasileva S.V. To study the anabolic aspects of lactation in cows in connection with the intensity of ketogenesis in the new body period. International Journal of Veterinary Medicine. 2023;(4):447-456. (In Russ.) https://doi.org/10.52419/issn2072-2419.2023.4.447