Changes in the gas composition of umbilical cord blood of newborns after cesarean section using various protocols of general anesthesia in dogs

Abstract

Cesarean section, being one of the most common  operations  in  veterinary  surgery, requires  a  special  anesthetic  protocol  that provides adequate anesthesia for the mother and has minimal effect on puppies. The aim of  the  study  was  to  evaluate  the  effect  of various non-inhalation and inhaled anesthetics on newborn puppies during cesarean section,  based  on  the  analysis  of  cord  blood gases.  3  groups  of  experimental  animals were formed, which used one of the studied anesthetic protocols. In the first experimental group, propofol at a dose of 4-6 mg/kg was used to maintain general anesthesia. Inhaled halogen-containing anesthetics were used in the  second  and  third  experimental  groups. Isoflurane 0.5 – 2.0 vol% was  used  in  the second  group,  and  sevoflurane  1.0  –  2.0 vol%  was  used  in  the  third  group.  When using  all  the  studied  anesthetics,  an  acidbase imbalance in the form of moderate acidosis was detected in the puppies after delivery, however, acidosis was less pronounced in the groups where halogen-containing anesthetics were used. The use of inhaled halogen-containing anesthetics had a lesser effect on puppies compared to non-inhalation ones. There were no significant differences in the effect  of  isoflurane  and  sevoflurane  from inhaled anesthetics.