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International Journal of Veterinary Medicine

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The effectiveness of feed additives in chronic kidney disease in cats

https://doi.org/10.52419/issn2072-2419.2023.4.507

Abstract

Chronic kidney disease in cats is one of the most common diseases. The main direction of palliative therapy for chronic kidney disease  and  extending  the  survival  time  of cats  is  to  limit  phosphates  in  the  diet  and normalize the phosphorus content in the animal’s body. In order to reduce phosphates, phosphate  binders  are  used  -  substances whose mechanism of action is to bind excess phosphate  ions  in  the  gastrointestinal  tract, which  prevents  their  entry  into  the  blood-stream. The purpose of the study is to analyze  the  effectiveness  of  feed  additives “Urdetox” and “Ipakitine” in a comparative aspect in the palliative treatment of chronic kidney disease in cats. Determination of the biological activity of the proposed feed additive for cats with CKD in the form of tablets was  carried  out  on  the  basis  of  veterinary clinics in the city. Volgograd, St. Petersburg, Moscow, in the period 2021-2022. The objects  of  the  study  were  cats  whose  owners complained of loss of animal body weight, often  a  general  depressed  state,  decreased appetite,  periodic  vomiting,  frequent  urination, dull hair. The diagnosis and experiment were  carried  out  by  collecting  anamnestic data, determining clinical signs and laboratory data - a general urine test and a biochemical  analysis  of  blood  serum.  Studies  have shown that feed additives containing a phosphate binder and a detoxicant help eliminate the  main  clinical  manifestations  of  chronic renal failure. The introduction of the essential amino acid -taurine into the feed additive in the form of Urdetox tablets, as well as the accuracy of dosing and ease of use increase the effectiveness of its biological action.

About the Authors

S. N. Fedotkina
Volgograd State Medical University
Russian Federation

Candidate of Veterinary Sciences



A. N. Shinkarenko
Volgograd State Medical University
Russian Federation

Doctor of  Veterinary  Science,  Professor



O. G. Strusovskaya
Volgograd State Medical University
Russian Federation

Doctor of Pharmaceutical Sciences, Associate Professor



References

1. Yerlepesova P. M., Maksudova M. H., Mukhiddinova N. Z. Studying the membrane-protective efficacy of taurine in clinical conditions //Biology and integrative medicine. - 2017. – No. 2. – pp. 34-41.

2. Koba, I. S., Lifentsova, M., Novikova, E. N., & Glushchenko, S. G. Analysis of manifestations of urolithiasis in cats // Polythematic online electronic scientific journal of the Kuban State Agrarian University. – 2018. – No. 135. pp. 1-11

3. Larionova O. S.] and others. The use of chitosan in the complex therapy of chronic renal failure in cats and dogs //Rabbit breeding and animal husbandry. – 2017. – №. 6. – Pp. 25-28.

4. Plavskikh O. V., Degtyareva E. O., Kopylovich M. V. The use of phosphate binders in chronic renal failure in cats // Actual problems of veterinary science and practice. – 2021. – pp. 166-169.

5. Ryadchikova O. L. Peculiarities of cats' nutritional needs //Polythematic online electronic scientific journal of the Kuban State Agrarian University. - 2020. – No. 163. – pp. 1-22.

6. Ushakova T. M., Derezina T. N. Correlation of morphofunctional disorders of the hepatorenal system and the level of redox homeostasis in chronic renal failure in cats // Current issues of veterinary biology. – 2021. – №. 4 (52). – Pp. 20-27.

7. Anraku M. et al. The effect of chitosan on oxidative stress and related factors in hemodialysis patients //Carbohydrate polymers. - 2014. – vol. 112. – pp. 152-157.

8. ISFM consensus recommendations for the diagnosis and treatment of chronic kidney disease in cats // J. Feline Med. Surgery. -2016. – Volume 18. – pp. 219-239.

9. Ripps H., Shen W. taurine: a “very essential” amino acid //Molecular vision. – 2012. – vol. 18. – p. 2673.


Review

For citations:


Fedotkina S.N., Shinkarenko A.N., Strusovskaya O.G. The effectiveness of feed additives in chronic kidney disease in cats. International Journal of Veterinary Medicine. 2023;(4):507-514. (In Russ.) https://doi.org/10.52419/issn2072-2419.2023.4.507

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ISSN 2072-2419 (Print)