Features of the colostral immunity formation in the newborn calves obtained from the cows with extragenital pathology
M. S. Zhukov,
P. A. Parshin,
G. A. Vostroilova,
I. T. Shaposhnikov,
Yu. N. Brigadirov,
Yu. N. Alekhin https://doi.org/10.52419/issn2072-2419.2024.3.95
Abstract
The objective of our research was to study the features of the colostral immunity formation in the newborns obtained from the cows with different clinical conditions during gestation. The object of the study was Red-Motley cows (n=28) in the third trimester of gestation and the newborn calves obtained from them. Group I – clinically healthy (control, n=8), group II – animals with hepatodystrophy (n=6), group III – animals with a combined course of hepatodystrophy and anemia (n=14). It has been found that in the cows with liver pathology and/or anemia, the colostrum of the first milk yield contains less protein and immunoglobulins by 24.1-25.4% and 11.9-14.2% (P ˂ 0.05), respectively. However, it was noted that in the calves obtained from the cows of group II, the blood serum content of total immunoglobulins after colostrum feeding did not differ from the values of the control group, while in the calves obtained from the cows of group III, the same indicator was lower by 43.0% (P ˂ 0.05). To clarify the reasons for this phenomenon, the Spearman correlation analysis was carried out, which showed that the level of total immunoglobulins in colostrum did not have a significant effect on their amount in the blood serum of calves after colostrum feeding (Rs = 0.40, P ˃ 0.05). In this case, the presence of anemia in calves was of decisive importance (Rs = 0.77, P ˂ 0.05). Thus, the formation of colostral immunity in calves depends not only on the quality of colostrum, but also on the clinical status of the newborn and in particular the presence of a hypoxic and acedotic condition.
About the Authors
M. S. Zhukov
All-Russian Scientific Research Veterinary Institute of Pathology, Pharmacology and Therapy
Russian Federation
Russian Federation
Zhukov M.S. – cand. veterinarian. sciences, art. sci. sotr. Department of Experimental Pharma-cology and Functioning of Living Systems
P. A. Parshin
All-Russian Scientific Research Veterinary Institute of Pathology, Pharmacology and Therapy
Russian Federation
Russian Federation
Parshin P.A. – Doctor of Veterinary Sciences, Professor, Director
G. A. Vostroilova
All-Russian Scientific Research Veterinary Institute of Pathology, Pharmacology and Therapy
Russian Federation
Russian Federation
Vostroilova G.A. – Doctor of Biological Sciences, Chief Scientific Officer. sotr. Department of Experimental Pharmacology and Functioning of Living System
I. T. Shaposhnikov
All-Russian Scientific Research Veterinary Institute of Pathology, Pharmacology and Therapy
Russian Federation
Russian Federation
Shaposhnikov I.T. – Doctor of Biological Sciences, Chief Scientific Officer. sotr. Department of Experimental Pharma-cology and Functioning of Living Systems
Yu. N. Brigadirov
All-Russian Scientific Research Veterinary Institute of Pathology, Pharmacology and Therapy
Russian Federation
Russian Federation
Brigadirov Yu.N. – Doctor of Veterinary Sciences, Chief Scientific Officer. sotr. Department of Experimental Pharmacology and Function-ing of Living Systems
Yu. N. Alekhin
All-Russian Scientific Research Veterinary Institute of Pathology, Pharmacology and Therapy
Russian Federation
Russian Federation
Alekhin Yu.N., Doctor of Veterinary Sciences, Chief Scientific Officer. sotr. Department of Experimental Therapy
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Review
For citations:
Zhukov M.S., Parshin P.A., Vostroilova G.A., Shaposhnikov I.T., Brigadirov Yu.N., Alekhin Yu.N. Features of the colostral immunity formation in the newborn calves obtained from the cows with extragenital pathology. International Journal of Veterinary Medicine. 2024;(3):95-107. (In Russ.) https://doi.org/10.52419/issn2072-2419.2024.3.95
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