Features of antimuller hormone concentration and biochemical parameters of blood of donor cows in the follicular phase of the reproductive cycle
https://doi.org/10.52419/issn2072-2419.2025.2.357
Abstract
Determining the follicular phase of the estrous cycle is a critical task for successful artificial insemination, embryo transplantation, and egg washing in cows. The existing methods for determining this period are not ideal and have a number of limitations. Laboratory diagnostics plays a key role in modern animal husbandry. Monitoring of reproductive status, monitoring of metabolic processes, and assessment of feeding quality are critical control points during both routine medical examinations and specialized examinations of high–value animals. For the most part, reproduction control may consist in determining progesterone levels, diagnosing anestrus, and identifying the most optimal time for insemination. One of the markers of routine assessment of reproductive status may be the anti-muller hormone. Determining the level of anti-Muller hormone (AMH) seems to be a promising tool for monitoring reproductive status, especially in large herds, however, additional study of this hormone is required for a more accurate understanding. In the presented study, the biochemical parameters of the blood of 9 Holstein cows in the follicular phase were analyzed. A high degree of direct correlation was found between the AMH level and serum creatinine and phosphorus levels (0.75 and 0.78, respectively). An inverse correlation of a noticeable degree (-0.63) was found between the level of AMH and the level of serum AsAt activity. The study of the synthesis, regulation and metabolic effect of AMH continues, data on its relationship with other regulatory factors are limited. Additional research is needed to better understand this correlation and its significance.
About the Authors
A. I. KozitsynaRussian Federation
Candidate of Veterinary Sciences, Associate Professor
L. Yu. Karpenko
Russian Federation
Doctor of Biological Sciences, Professor
G. S. Nikitin
Russian Federation
Candidate of Veterinary Sciences, Associate Professor
V. V. Achilov
Russian Federation
Candidate of Veterinary Sciences, Assistant
V. A. Olontsev
Russian Federation
postgraduate student
V. S. Semenova
Russian Federation
postgraduate student
References
1. Bugrov, A.D. Growth and development of follicles in spontaneous and induced sexual cycles in cows with prostaglandin (PGF2 α), native and prolonged FSH / A.D. Bugrov // Scientific and Technical Bulletin of the Institute of Animal Husbandry of the National Academy of Agrarian Sciences of Ukraine. – 2011. – No. 105. – pp. 24-37. – EDN SLQXEH.
2. Vshivtseva, A. I. Neurohumoral regulation of sexual function in cattle and its relation to ovarian pathology / A. I. Vshivtseva, N. B. Nikulina // Youth Science 2024: technologies of innovation : Proceedings of the All-Russian scientific and practical conference of young scientists, graduate students and students dedicated to the Decade of Science and Technology in the Russian Federation. In 4 parts, Perm, April 08-12, 2024. – Perm: CPI Procrost, 2024. – pp. 24-27. – EDN IDJRLR.
3. Machakhtyrov, G. N. Investigation of the functional state of cow ovaries by ultrasound scanning / G. N. Machakhtyrov, V. A. Machakhtyrova // Achievements of science and technology of the agroindustrial complex. – 2020. – Vol. 34, No. 1. – pp. 48-51. – DOI 10.24411/0235-2451-2020-10109. – EDN JJNZPT.
4. Modification of the stages of vitrification technology of Bos taurus oocytes / T. I. Kuzmina, I. V. Chistyakova, I. P. Sheiko, A. I. Ganzha // Tauride Bulletin of Agrarian Science. – 2017. – № 3(11). – Pp. 80-87. – EDN ZWQSTJ.
5. Nemtsova, A. S. The effect of the drug "Surfagon 50" on folliculogenesis in cows during lactation / A. S. Nemtsova, A. A. Garbuzov, E. A. Yushkovsky // Issues of regulatory regulation in veterinary medicine. – 2020. – No. 1. – pp. 147-149. – DOI 10.17238/issn2072-6023.2020.1.147. – EDN CJRKHX.
6. Reproductive function of cows (Bos taurus) under the influence of various kisspeptins (review) / G. V. Shiryaev, A. O. Prituzhalova, G. S. Nikitin [et al.] // Agricultural Biology. – 2023. – Vol. 58, No. 6. – pp. 974- 989. – DOI 10.15389/agrobiology.2023.6.974rus. – EDN ZUGHAQ.
7. Statistical assessment of the concentration of antimuller hormone and biochemical parameters of blood of donor cows in the luteal phase of the cycle / A. I. Kozitsyna, L. Y. Karpenko, G. S. Nikitin [et al.] // International Bulletin of Veterinary Medicine. – 2023. – No. 4. – pp. 221-226. – DOI 10.52419/issn2072-2419.2023.4.221. – EDN GUMSBK.
8. Khusnetdinova, N. F. An approach to the diagnosis of obesity in sheep / N. F. Khusnetdinova, B. S. Ilchiev // Collection of scientific papers of the Krasnodar Scientific Center for Animal Science and Veterinary Medicine. – 2022. – Vol. 11, No. 1. – pp. 219-222. – DOI 10.48612/sbornik-2022-1-54 . – EDN GUOCQM.
9. Blood biochemical markers in Saanen goats depending on month of pregnancy / A. Taraskin, A. Bakhta, L. Karpenko [et al.] // FASEB Journal. – 2021. – Vol. 35, No. S1. – P. 05198. – DOI 10.1096/fasebj.2021.35.S1.05198. – EDN JSVGFR.
10. Mossa, Francesca, and James J Ireland. “Physiology and endocrinology symposium: Anti-Müllerian hormone: a biomarker for the ovarian reserve, ovarian function, and fertility in dairy cows.” Journal of animal science vol. 97,4 (2019): 1446-1455. doi:10.1093/jas/skz022.
11. Mycotoxin eliminator "Elitox" in lasttrimester pregnant cows application impact on immune blood profile of offspring / A. Kozitsyna, L. Karpenko, A. Bakhta [et al.] // Reproduction in Domestic Animals. – 2018. – Vol. 53, No. S2. – P. 153. – EDN YKVLIT.
12. Naniwa Y., Nakatsukasa K., Setsuda S., Oishi S., Fujii N., Matsuda F., Uenoyama Y., Tsukamura H., Maeda K.-i., Ohkura S. Effects of full-length kisspeptin administration on follicular development in Japanese black beef cows. Journal of Reproduction and Development, 2013, 59(6): 588-594 ( ). DOI: 10.1262/jrd.2013-064
13. Pregnant Cows and Heifers Blood Profile Comparison / A. I. Kozitsyna, L. Yu. Karpenko, A. A. Bakhta [et al.] // International scientific and practical conference "Agro-SMART - Smart solutions for agriculture" (Agro-SMART 2018), Tyumen, July 16-20, 2018. Vol. 151. – Tyumen: Atlantis Press, 2018. – P. 391-396. – EDN ZCDCWT.
Review
For citations:
Kozitsyna A.I., Karpenko L.Yu., Nikitin G.S., Achilov V.V., Olontsev V.A., Semenova V.S. Features of antimuller hormone concentration and biochemical parameters of blood of donor cows in the follicular phase of the reproductive cycle. International Journal of Veterinary Medicine. 2025;(2):357-363. (In Russ.) https://doi.org/10.52419/issn2072-2419.2025.2.357