Preventive use of probiotic supplement "Hydrolaktiv" in calves with gastrointestinal diseases and its effect on the formation of the intestinal microbiome

The aim of the study was to study the preventive efficacy of the probiotic supplement "GidroLaktiV" and to establish its effect on the formation of the intestinal microbiome in calves with neonatal gastrointestinal diseases. The object of the study was healthy newborn calves that did not have clinical signs of hypotrophy. From the selected calves, according to the principle of analogues, taking into account body weight and physiological condition, two groups were formed – the control and the experimental. Each of the groups included ten animals. The animals of both groups were kept in identical conditions on a basic diet adopted by the farm for raising young animals. From the fourth day of life until the age of forty, calves of all groups were given kefir prepared using the enzymatic feed additive "GastroVet" according to the scheme adopted in the experimental farm. Additionally, the feed additive "GidroLaktiV" was added to kefir to the calves of the second experimental group at a dose of 15.0 g per head twice a day. In the case of clinical signs of gastrointestinal diseases in the studied animals, primarily manifested by dyspepsia, they were treated according to the scheme used in the farm. The last one included: "Coliflox" at a dose of 2.0 ml / goal / day; "Sulfetrisan" at a dose of 3.0 ml / goal / day; 9-valent serum (Uralbiovet), once at a dose of 50.0 ml / goal. The treatment was carried out until the clinical signs completely disappeared. In order to assess the degree of influence of the additive used on the composition of the intestinal microflora, stool samples were examined using a bacteriological method. The conducted studies have shown high preventive effectiveness from the use of the probiotic supplement "GidroLaktiV", which is characterized by a decrease in the incidence rate and a shortening of the recovery time. The supplement used has a positive effect on the formation of the intestinal microbiome of calves. This is manifested by a decrease in the amount of E. coli and staphylococcus in its composition, which indicates its antagonistic activity to conditionally pathogenic flora, as well as an increase in the level of lactobacilli.

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