State of humoral defense mechanisms in piglets of different age groups under non-specific bronchopneumonia

Abstract

Respiratory diseases in pigs are widespread. They cause great economic damage to farms, it is summed up both from the culling and death of animals in different age periods, and from a decrease in weight gain against the background of chronic hypoxia. The incidence of non-specific bronchopneumonia in pigs in some farms can reach 80%. Violation of zoohygienic conditions of detention contributes to morbidity. The aim of the study was to study the state of some indicators of the innate and adaptive immune response in non - specific pneumonia in sick piglets and healthy piglets of different age groups-suckling piglets, piglets of rearing and fattening groups kept in a large pig complex. As a result of research, it was found that all piglets with bronchopneumonia have a violation of the protective mechanisms of the innate and adaptive immune links. During all periods of the study, impaired antibody synthesis was observed. The humoral mechanisms of innate immunity were significantly weakened. In our opinion, it is the defect of humoral innate mechanisms that can contribute to the occurrence and maintenance of the inflammatory process in the lungs.