Preview

International Journal of Veterinary Medicine

Advanced search

Determination of the level of specific immunoglobulin e in the blood of cats with obstructive bronchitis with an allergenic component

https://doi.org/10.17238/issn2072-2419.2020.3.154

Abstract

The article presents the results of blood testing of cats with obstructive bronchitis for specific immunoglobulin E in order to confirm the allergic etiology of the disease. The study involved 16 animals, of which an increased level of specific IgE was detected in 12 animals, 1 cat had uncertaine result, and only 3 animals showed a level within the physiological norm. Comparing the obtained results with the data of allergic skin intradermal testing, it can be seen that the largest number of registered allergic reactions is associated with a high level of specific immunoglobulin E in the blood serum of animals, immunized by antigens, coming from the environment. That is, the antigens of house dust mites, especially mites of the genus Dermatophagoides farinae and Dermatophagoides Pteronyssinus. Thus, the proportion of animals that had an allergic reaction to these ticks was 56.3 %. We observed slightly lower allergenicity for ticks of the genus Tugorhadis putrescentiae (37.5 %), Acarus siro (37.5%). Less than 7 % of allergic reactions were observed to antigens of herbs, in particular, meadow thymothy (phelum pretense), white Marion (Chenopodium album L.) and plantain major (Plantago major). There was no immunological reaction to plant components: hazel (Corylus), common wormwood (Artemisia vulgaris). The results obtained using enzyme immunoassay (ELISA) were highly common with the results obtained during intra-dermal allergen testing. We can conclude that determining the level of IgE immunoglobulin in the blood of cats with signs of OB is an objective diagnostic criterion for confirming the allergic nature of obstructive bronchitis in cats.

About the Authors

L. I. Sabirzyanova
FGBU “Saint-Petersburg State University of Veterinary Medicine”
Russian Federation


V. V. Kryukova
FGBU “Saint-Petersburg State University of Veterinary Medicine”
Russian Federation


References

1. Герке, В. С. Диагностический подход к кашлю / В. С. Герке // VetPharma. - 2012. - № 5. - С. 30-34.

2. Горячкина, Л. А. Клиническая аллергология и иммунология: руководство для практикующих врачей / Л. А. Горячкина, К. П. Кашкин. - М.: Миклош, 2009. -432 с.

3. Козицына А.И., Карпенко Л.Ю., Бахта А.А, Особенности показателей крови кошек при афаниптерозе (блошином аллергическом дерматите)/ Материалы III международного паразитологического симпозиума. 2019.с.140-142.

4. Пернас, Х. С. Астма кошек / Х. С. Пернас // Veterinary Focus. - 2010. - Vol. 20. - № 2. - Р. 10-17.

5. Руппель, В. В. Применение иммуно-ферментного анализа (ИФА) при диагностике аллергических заболеваний у собак и кошек / В. В. Руппель // Ветеринарный Петербург. - 2012. - № 3. - С. 21 -25.

6. Справочник ветеринарного терапевта: учебное пособие для студентов высших учебных заведений, обучающихся по специальности 111201 - "Ветеринария" / под ред. Г. Г. Щербакова. - Изд. 5-е, испр. и доп. - СПб.: Лань, 2009. - 655 с.

7. Foster, A. P. Comparison of intradermal and serum testing for allergen-specific IgE using a Fce-RIa-based assay in atopic dogs in the UK / A. P. Foster, J. D. Littlewood, P. Webb [et al.] // Veterinary Immunology and Immunopathology. - 2003. - Vol. 93. -P. 51-60.

8. Lee-Fowlera, T. M. Comparison of intra-dermal skin testing (IDST) and serum allergen-specific IgE determination in an experimental model of feline asthma / T. M. Lee-Fowlera, L. A. Cohna, A. E. DeCluea [et al.] // Veterinary Immunology and Immunopathology. - 2009. - Vol. 132 (1). -P. 46-52.


Review

For citations:


Sabirzyanova L.I., Kryukova V.V. Determination of the level of specific immunoglobulin e in the blood of cats with obstructive bronchitis with an allergenic component. International Journal of Veterinary Medicine. 2020;(3):154-157. (In Russ.) https://doi.org/10.17238/issn2072-2419.2020.3.154

Views: 276


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2072-2419 (Print)