Features of changes in the biochemical composition of calves ’ blood in early postnatal ontogenesis

Abstract

The study of the biochemical composition of blood in animals is one of the methods for assessing the physiological state of the body. Changes in biochemical parameters can be both pathological and adaptive-age (physiological) in nature. A group of 18 clinically healthy animals was formed to determine the dynamics of the biochemical composition of blood in newborn calves. Blood was obtained immediately after birth, on the 1.7 and 14 days of life. The results of research showed that 24 hours after drinking the first portion of colostrum, there are no significant changes in the biochemical composition of the blood, and after the first and second weeks of life, changes occur in a number of indicators. Thus, the increase in the level of total protein by day 14 was 6.4%, albumin 13.7%, and albumin -globulin coefficient 19.7%. Nitrogen metabolism was characterized by an increase in urea concentration in the blood by 34.3%, a decrease in creatinine level by 23.8% AST activity by 3.9 times, ALT by 2.5 times, and the de Ritis coefficient by 2.8 times. Also, by the 14th day of life, there was a decrease in the activity of alkaline phosphatase by 30.0% glucose level by 21.1%, total bilirubin by 5.3 times, and the concentration of substances of medium and low molecular weight by 24.2%. The dynamics of macronutrients was characterized by an increase in calcium by 28.6%, phosphorus by 4.2 times, and magnesium by 30 times. By the seventh day of life, calves had a 32.5% decrease in iron levels, and by the second week the indicator decreased by 2.9 times. Thus, in the first two weeks of life, calves have pronounced changes in nitrogen and mineral metabolism. The dynamics of trace elements is characterized by a decrease in the level of iron, which requires correction of its intake into the body.