Abstract
The aim of the study was to study the effect of complex biologically active substances on the body of piglets. The material for the study was a new drug, Rigatirin. This drug is unique in its composition, and its plant components and enterosorbents have detoxification, antimicrobial, anti-inflammatory properties. In addition, to increase the activity of the adaptogenic action of the new phytosorption complex, the drug Marimix 5: 0 was used together, which has already established itself as a drug with growth-promoting and anti-stress effects. 4 groups of animals were created (n = 10). Age 2-3 months. The duration of the experiment was 14 days. Animals of the first and second groups, in addition to the basic diet, added the drug rigatirin, at a dose of 1 g / kg, for 14 days. Additionally, the second group of piglets were injected with the drug marimix 5: 0 at a dose of 0.2 ml / kg. The course was 5 days. Animals of the third group were injected with only the drug marimix 5: 0 at a dose of 0.2 ml / kg for 5 days. Animals of the fourth group did not administer drugs, and the pigs received only the basic diet according to physiological norms. Throughout the experiment, a daily clinical examination was performed: thermometry, massimetry were performed, and the conditions of the skin and mucous membranes were assessed. To study the pharmacological activity of the drug and its effect on the body of the young, a biochemical and clinical blood analysis was performed. An assessment was made of feed consumption, degree of appetite and watering regime. On the basis of the tests carried out, it is possible to judge the positive effect of biologically active substances on the natural resistance of the young, which indicates a better adaptation ability of weaned piglets to the adverse effects of post-release stress, and, consequently, intensive growth in this period. So the level of bactericidal activity increased by 6.6%, against these indicators in the control group. In turn, the level of immunoglobulins increased by 18.6%, and the level of phagocytic activity by 6.2%, compared with animals who were not given any additives in the diet.