The study of postvaccinal reactions in animals immunized against brucellosis is conjunctival

The work purpose - to study vaccine-challenged reactions after use of vaccines from strains of B.abortus19 and B.abortus 82 by a conjunctival method in experience on cattle of economy, safe on a brucellosis.For carrying out researches on comparative studying of vaccine-challenged reactions after use of vaccines from strains of B.abortus19 and B.abortus 82 the conjunctival method on cattle has created two groups of animals - bulls, economy, safe on a brucellosis, at the age of 1,5-2 years which aren't imparted earlier only 64 heads. Blood serums from immunized animal all groups investigated by the standard methods according to "Manual on diagnosis of a brucellosis of animals" (2014) in reactions: the roses bengal test (RBT), the agglutination reaction (AR) and reaction of binding of a complement with "A set of components for diagnosis of a brucellosis of animals in RA, RSK, RDSK" with uniform brutsellezny antigen (S) and R-antigen, reactions of immunodiffusion (RID) with O-PS antigens.At animals immunized B.abortus 82, noted reactions throughout the entire period of a research (90 days), including in high credits, both with S-, and with R-antigens. At conjunctival immunization of animals vaccine from B.abortus 19 strain for the 30th days in serums of blood has revealed the agglutinating and komplementsvyazyvayushchy antibodies with S-antigen in low credits at 21 animals that has made 65% of total in group, and by 60 days they completely disappear. It is established that conjunctival use of vaccine from a strain of B.abortus19 allows to provide the high level of immunity to brucellas at animals and to freely carry out diagnostics of animals.

крупный рогат ый скот , бруцеллез , иммунизация , конъюнкт иваль-ный метод , посвакцинальные реакции , cattle , brucellosis , immunization , con-junctivalmethod , postvaccinalreactions

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