Clinical and therapeutic significance of microbiota in purulent-inflammatory processes in animals
https://doi.org/10.17238/issn2072-2419.2021.1.286
Abstract
The article presents data on the diagnostic value of the indigenous microbiota in providing colonization resistance of the body in inflammatory processes. It is shown that the probiotic microbiota in the body of animals forms a stable colonization resistance, which prevents the development of various dysbiotic disorders that cause the occurrence of pathologies. The totality of microorganisms in the body's biotopes should be considered as an integral microbial ecosystem. Conditionally pathogenic microorganisms can remain in the microbial ecosystem, in such quantities that do not pose a great danger to their host. However, the development of adverse factors leads to a violation of the ecological system and, accordingly, leads to a change in the balance between the obligate and facultative microbiota. Often, an increase in the number of conditionally pathogenic microorganisms leads to the development of the disease, or its complication. Therefore, to effectively combat purulentinflammatory processes, it is necessary to form optimally balanced microbiocenoses in the body's biotopes with the help of biological products. The use of probiotics in the complex treatment of purulent-inflammatory processes is an evolutionarily justified approach, which requires further study to determine the indications for their widespread use.
About the Authors
Yu. A. Vatnikov
Department of Veterinary Medicine, Agrarian Technological Institute, Peoples’ Friendship University of Russia (RUDN University)
Russian Federation
Russian Federation
Doctor of Veterinary Science, professor,
Moscow
P. A. Rudenko
Department of Veterinary Medicine, Agrarian Technological Institute, Peoples’ Friendship University of Russia (RUDN University);
Biological Testing Laboratory, Branch of Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences (BIBCh RAS)
Russian Federation
Russian Federation
Doctor of Veterinary Science, associate professor, Moscow;
Pushchino, Moscow region
A. A. Rudenko
Department of Veterinary Medicine, Moscow State University of Food Production
Russian Federation
Russian Federation
Doctor of Veterinary Science, professor,
Moscow
E. V. Kulikov
Department of Veterinary Medicine, Agrarian Technological Institute, Peoples’ Friendship University of Russia (RUDN University)
Russian Federation
Russian Federation
PhD of Vet Sc., associate professor,
Moscow
V. I. Kunetsov
Department of Veterinary Medicine, Agrarian Technological Institute, Peoples’ Friendship University of Russia (RUDN University)
Russian Federation
Russian Federation
Doctor of Medicine Science, professor,
Moscow
S. B. Seleznev
Department of Veterinary Medicine, Agrarian Technological Institute, Peoples’ Friendship University of Russia (RUDN University)
Russian Federation
Russian Federation
Doctor of Veterinary Science, professor,
Moscow
References
1. Паразитоценозы животных. Учебное пособие. / А.Ф. Руденко, А.М. Ермаков, А.А. Руденко и др. – Ростов-на-Дону, 2020 – 510 с.
2. Патогенетические особенности воспалительных процессов у кошек: монография / П.А. Руденко, Ю.А. Ватников, А.А. Руденко и др. – Москва: РУДН, 2020. – 219 с.
3. Руденко, П.А. Интенсивность перекисного окисления липидов и активность антиоксидантной системы кошек при гнойно-воспалительных процессах / П.А. Руденко // Ветеринария. – 2016. – №10. –С. 45-48.
4. Руденко, П.А. Механизмы формирования микробиоценозов, совершенствование методов диагностики, профилактики и лечения представителей семейства кошачьих при хирургических инфекциях / Диссертация на соискание ученой степени доктора ветеринарных наук / МГАВМиБ – МВА имени К.И. Скрябина. Луганск, 2018.
5. Руденко, П.А. Патогенетические особенности течения хирургических инфекций у представителей семейства кошачьих / П.А. Руденко // Ветеринария, зоотехния и биотехнология. –№3. – 2017. –С. 17-24.
6. Руденко, П.А. Проведение доклинических испытаний пробиотико-сорбционных препаратов «Дилаксил» и «Сорбелакт» / П.А. Руденко, А.Н. Мурашев // Биофармацевтический журнал. – 2017. – 9(3). –С. 49-54.
7. Руденко, П.А. Роль дисбактериоза кишечника в механизмах формирования и прогрессирования хирургической инфекции у кошек / П.А. Руденко // Научная жизнь. – 2018. – №1. –С. 84 -98.
8. Руденко, П.А. Технологический процесс производства комплексных пробиотикосорбционных препаратов «Дилаксил» и «Сорбелакт» / П.А. Руденко, А.Н. Мурашев // Биофармацевтический журнал. – 2017. – 9(6). – С. 40-45.
9. Руденко, П.А. Цитологическая характеристика случайных гнойных ран у кошек в динамике их лечения / П.А. Руденко // Вестник Ульяновской государственной сельскохозяйственной академии. – 2016. – №3(35). –С. 134-141.
10. Руденко, П.А. Уровень морфобиохимических воспалительных маркеров при операционной травме у кошек / П.А. Руденко // Ветеринария, зоотехния и биотехнология. – 2017. – №1. –С. 18-24. 11. Al-Mohrej, O.A. Surgical treatment of adoles cent idiopathic scoliosis: Complications / O.A. AlMohrej, S.S. Aldakhil, M.A. Al-Rabiah et. аl // Ann. Med. Surg. – 2020. – 52. – Р. 19-23.
11. Ankawi, G. What Have We Learned about the Use of Cytosorb Adsorption Columns? / G. Ankawi, Y. Xie, B. Yang et. аl // Blood Purif. – 2019. – 48(3). – Р. 196-202.
12. Berger, M.M. Effect of intraoperative high oxygen concentrations on surgical site infection / M.M. Berger, F. Macholz, V. Tangel et. аl // J. Hosp. Infect. – 2016. – 94(2). – Р. 206-207.
13. Bilyayeva, O. Effects of SertaSil on wound healing in the rat / O. Bilyayeva, V.V. Neshta, A. Golub et. аl // J. Wound Care. – 2014. – 23(8). – Р. 410-414.
14. Ding, X.X. Clinical observation of soft palatepharyngoplasty in the treatment of obstructive sleep apnea hypopnea syndrome in children / X.X. Ding, L.Q. Zhao, X.G. Cui et. аl // World J. Clin. Cases. – 2020. – 8(4). – Р. 679-688.
15. Duan, W. Cytocompatibility and osteogenic activity of a novel calcium phosphate silicate bioceramic: Silicocarnotite / W. Duan, C. Ning, T. Tang // J. Biomed. Mater. Res. A. – 2013. – 101(7). – Р. 1955-1961.
16. Formoso, P. Nanotechnology for the Environment and Medicine / P. Formoso, R. Muzzalupo, L. Tavano et. аl // Mini Rev. Med. Chem. – 2016. – 16(8). – Р. 668-675.
17. Fry, D.E. Prevention of Infection at the Surgical Site / D.E. Fry // Surg. Infect. – 2017. – 18(4). – Р. 377-378.
18. Ilatovskii, D.A. Holographic sol-gel monoliths: optical properties and application for humidity sensing / D.A. Ilatovskii, V. Milichko, A.V. Vinogradov // R. Soc. Open. Sci. – 2018. – 5(5). – Р. 172.
19. Mohammadi, S. Elimination of Cs+ from aquatic systems by an adsorbent prepared by immobilization of potassium copper hexacyanoferrate on the SBA-15 surface: kinetic, thermodynamic, and isotherm studies / S. Mohammadi, H. Faghihian // Environ. Sci. Pollut. Res. Int. – 2019. – 26 (12). – Р. 12055-12070.
20. Park, J.U. Acceleration of the healing process of full-thickness wounds using hydrophilic chitosan -silica hybrid sponge in a porcine model / J.U. Park, S.H. Jeong, E.H. Song et. аl // J. Biomater. Appl. – 2018. – 32(8). – Р. 1011-1023.
21. Rudenko, P. Biocoenotic Diagnostics of Unfavorable Factors in the Cows Infection of Farms in the Moscow Region / P. Rudenko, V. Rudenko, Yu. Vatnikov et. аl // Systematic Reviews in Pharmacy. – 2020. – 11(5). – Р. 347-357.
22. Rudenko, P. Experimental and clinical justification of the use of probiotic-sorption drugs in veterinary surgery / P. Rudenko, Yu. Vatnikov, E. Kulikov et. аl // Systematic Reviews in Pharmacy. – 2020. – 11(4). – Р. 275-287.
23. Rudenko, P.A. The effectiveness of probioticsorption compounds in the complex treatment of sepsis in cats / P.A. Rudenko, V.B. Rudenko, A.A. Rudenko et. аl // Research J. of Pharmaceutical, Biological and Chemical Sciences. – 2019. – 10(1). – Р. 1734-1739.
24. Smolentsev, S. Yu., Influence of paraaminobenzoic acid on young cattle / S.Yu. Smolentsev, A.H. Volkov, E.K. Papunidi et. аl // International Journal of Research in Pharmaceutical Sciences. – 2020. – 11(2). – Р. 1481-1485.
25. Vatnikov, Yu. Effectiveness of biologically active substances from Hypericum Perforatum L. in the complex treatment of purulent wounds / Yu. Vatnikov, S. Shabunin, E. Kulikov et. аl // International Journal of Pharmaceutical Research. – 2020. – 12(4). – Р. 1108-1117.
26. Vatnikov, Yu. Antimicrobial activity of Hypericum Perforatum L. / Yu. Vatnikov, S. Shabunin, A. Karamyan et. аl // International Journal of Pharmaceutical Research. – 2020. – 12(S.1). – Р. 722-730.
27. Wu, Q.J. Effects of clinoptilolite and modified clinoptilolite on the growth performance, intestinal microflora, and gut parameters of broilers / Q.J. Wu, L.C. Wang, Y.M. Zhou et. аl // Poult. Sci. – 2013. – 92 (3). – Р. 684-692.
28. Yu, L. A tightly-bonded and flexible mesoporous zeolite-cotton hybrid hemostat / L. Yu, X. Shang, H. Chen et. аl // Nat. Commun. – 2019. – 10(1). – Р. 1932.
Review
For citations:
Vatnikov Yu.A., Rudenko P.A., Rudenko A.A., Kulikov E.V., Kunetsov V.I., Seleznev S.B. Clinical and therapeutic significance of microbiota in purulent-inflammatory processes in animals. International Journal of Veterinary Medicine. 2021;(1):286-291. (In Russ.) https://doi.org/10.17238/issn2072-2419.2021.1.286
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