Effect of mitophen on hematological leukocyte indices of broiler chickens

Abstract

Hematological leukocyte indices provide additional information about intoxication and the state of the immune response and become an alternative to determine a number of immuno-biochemical parameters. The aim of the work is to study the effect of the antioxidant mitophen on the leukocyte indices of blood that characterize the nonspecific reactivity of the organism of broiler chickens. The chickens of the I and III experimental groups were given mitophen daily from the daily age at the rate of 25 and 50 g/t of feed for a month, the II and IV-25 and 50 g/t of feed only in the first and third weeks of the experiment. The control group received the main diet without the drug. The leukocyte indices were determined mathematically by the leukogram. It was found that the use of mitophen significantly increases the index: of shift of blood leukocytes, of the ratio of eosinophils and lymphocytes, and lowers the index of the ratio of lymphocytes and eosinophils, which indicates the positive effect of the drug on the granulocytopoiesis and nonspecific resistance of broiler chickens. At the same time, the use of mitophen significantly reduces index: of immunoreactivity, of the ratio of lymphocytes to monocytes, and pseudoeosinophils to monocytes, which characterizes the positive effect of the antioxidant on monocytopoiesis and nonspecific cellular immunity of the bird body due to monocytes.