Clinical and morphological features of intranasal neoplasms in dogs

The article describes the results of the study of intranasal neoplasms in dogs, their clinical and morphological characteristics, describes the variants of clinical manifestations of oncological diseases at different stages of development. The predisposition of dogs of dolichocephalic breeds to the development of the tumor process was revealed. The possible sexual predisposition of nasal cavity pathologies has been studied. Possible causes of carcinogenesis of nasal cavity tumors, the nature of which includes a significant number of factors, have been investigated. Various morphological diagnoses of nasal cavity pathologies in dogs have been studied. Data on the spread of intranasal neoplasms in dogs are presented on the example of 34 clinical cases of animals of different age groups with pathologies of the nasal cavity, with pronounced clinical symptoms and without symptoms. Clinical symptoms in animals with nasal cavity pathologies were evaluated and compared. The influence of exogenous and endogenous factors on the development and growth of malignant tumors was studied. The degree of spread and invasion was determined using such visual diagnostic methods as magnetic resonance imaging and computed tomography, the general condition of the animal was assessed using general clinical and biochemical blood tests. The clinical stage of the oncological process was determined based on the results of a clinical examination. The possibility of using therapeutic manipulations was evaluated and the risks were assessed. To determine the clinical stage of the malignant process, such methods of visual diagnostics as magnetic resonance and computed tomography, rhinoscopy, chest X-ray, ultrasonography of abdominal organs were used. The degree of malignancy of oncopathology and the final diagnosis were made on the basis of morphological studies (histological and immunohistochemical studies).

1. Добсон, Джейн М. Онкология собак и кошек / Джейн М. Добсон, Б. Ласцеллес, К. Дункан. - Москва: Изд-во «Аквариум», 2017. – С. 331-333.

2. Кулешова, Я.А. Опухоли носовой полости у собак и кошек: диссертация … канд. вет. наук: 16.00.02 / Кулешова Яна Александровна. – Москва, 2007 г. – 135 с.

3. Меликова, Ю.Н. Диагностика патологий носовой полости у собак и кошек / Ю.Н. Меликова, Я.А. Ягникова. – Москва: Изд-во «Офтальмология», 2021. – 164 с.

4. Морохоев, В.И. Ошибки в ранней диагностике злокачественных опухолей решетчатой кости. // «Вестник оториноларингологии», – 1990. №5. – С. 60-64.

5. Пачес, А.И. Опухоли головы и шеи. – М.: 2000, С.479.

6. Юрина, Н.А., Современные виды томографии // Н.А. Юрина, А.И. Радостина. – Санкт-Петербург: – 2006, – С. 131.

7. Douglas, S.W. Principles of veterinary radiography / S.W. Douglas, M.E. Herrtage, H.D. Williamson // Balliere Tindall, ed. 4. – London: 1987.

8. Haar, G.T. Diseases of the nose, nasal plane, nasal cavity and frontal sinus. World Congress WSAVA/FECAVA/CSAVA – Prague, 2006.

9. Harvey, C.E. The nasal septum of the dog: is it visible radiographically? / Colin E. Harvey // Journal of Veterinary Radiology. – 1979, – C. 20-28.

10. Holmberg, D.L. Ventral rhinotomy in the dog and cat. / D.L. Holmberg, C. Frites, J. Cockshutt // Journal of Veterinary Surgery. – 1989. №18. – С. 446-449;

11. MacEwen, E.G. Nasal tumors in the dog: retrospective evaluation of diagnosis, prognosis and treatment / E.G. MacEwen, S.J. Withrow, A.K. Patnaik // Journal of the American Veterinary Medical Association. – 1977. №170. – С. 45-48.

12. Patnaik, AK Canine sinonasal neoplasms: Clinicopathological study of 285 cases, J Am Anim Hosp Assoc 25. – 1989. – С.103–114