Preview

International Journal of Veterinary Medicine

Advanced search

Correction of post-stress disorders in rats in model experiments

https://doi.org/10.52419/ISSN2072-2419.2022.4.370

Abstract

The development of drugs to correct post -stress reactions, manifested by profound changes in homeostasis, is relevant for both human and veterinary medicine. The purpose of our study is to study the possibility of using the Klim organomineral supplement for the correction of post-stress disorders in rats in model experiments.
Wistar rats, four-month-old males weighing 350-400 grams, were used as the object of the study. For the study, animals were divided into 3 groups, intact, control and experimental were used to simulate stress reactions when exposed to low temperatures. Animals of the experimental group 21 days before the model experiments were given a daily Klim supplement with food .
The use of the Klim organomineral supplement to leveling the negative effects on blood morphological parameters when modeling acute stress, which is confirmed by our studies in production. Thus, it is possible to recommend the prophylactic use of the studied additive Klim in predicting a stressful situation of any origin (regrouping, cold, transportation).

About the Authors

O. V. Kryachko
St. Petersburg state university of veterinary medicine
Russian Federation

 doctor of veterinary science, professor 



L. A. Lukoyanova
St. Petersburg state university of veterinary medicine
Russian Federation

 associate professor 



References

1. Batrakov A. Prevention of metabolic disorders in cattle / Batrakov A., Plemyashov K., Kryachko O., Lukoyanova L. // Livestock in Russia. – 2021. – № 11. – P. 36-38.

2. Kosolapov, V. A. Simulation of stress in experiment / V. A. Kosolapov, I. A. Tregubova // Medicinal herald. – 2022. – Т.23. – № 2(86). – P. 17-19.

3. Kryachko, O.V. Correction of the functional state of the regulatory systems of the body of dogs under the influence of environmental stress factors/ Kryachko O.V., Lukoyanova L.A., Gaponova V.N. // International bulletin of veterinary medicine. – 2021. – № 4. – P. 172-176. – DOI 10.52419/issn2072-2419.2021.4.172.

4. Kryachko, O.V. The effect of klim feed additive on metabolic processes in cows after calving / Kryachko O.V., Lukoyanova L.A.// International bulletin of veterinary medicine – 2021. – № 4. – P. 185-189. – DOI 10.52419/issn2072-2419.2021.4.185.

5. Kryachko, O.V. Comparative assessment of models of experimental stress in rabbits by change of hematological and metabolic indicators / Kryachko O.V., Taran A.M. // Issues of regulatory and legal regulation in veterinary sectority. – 2018. – № 2. – P. 143-146.

6. Mitronin, A.V. Influence emotional-cold the stress on vascular endothelium of the pulp of cutters and oral mucous of rats / A.V. Mitronin, T.P. Vavilova, I.G. Ostrovskaya, Yu.G. Gaverova // Endodontiya Today. – 2013. – № 3. – P. 3-7.

7. Lukoyanova, L. Study of Adaptogenic Properties of the Drug Klim Pet Under Stress of Dogs in a Megalopolis / L. Lukoyanova, O. Kriyachko, V. Gaponova [et al.] // FASEB Journal. – 2021. – Vol. 35. – No S1. – P. 02469. – DOI 10.1096/fasebj.2021.35.S1.02469.


Review

For citations:


Kryachko O.V., Lukoyanova L.A. Correction of post-stress disorders in rats in model experiments. International Journal of Veterinary Medicine. 2022;(4):370-373. (In Russ.) https://doi.org/10.52419/ISSN2072-2419.2022.4.370

Views: 193


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2072-2419 (Print)