Results of a pilot study of the effect of bovhyaluronidaze azoximer on the incidence of complications after surgery manipulations on the urethra and the bladder in cats

According to our statistics, more than 20 % of the visiys of cat owners to veterinary clinics are related to various problems with the urinary system. Most of the animals with these problems are urological patients. We conducted a pilot study of the effect of Bovhyaluronidaze azoximer on the incidence of postoperative complications after bladder catheterization, cystotomy, perineal urethrostomy. The study was carried out on 50 cats after surgery manipulations on the urethra and the bladder. The cats were divided into two groups. The complex treatment for the ani mals of the experimental group (21 animals) included bovhyaluronidaze azoximer administration in the postoperative period. For the cats of the control group (29 animals) were done only standard complex treatment. The difference in the incidence of postoperative complications was evaluated using biostatistics methods: Pearson’s chi-squared test and Fisher's exact criterion. The analysis of the results of the pilot study showed that there is a statistically significant relationship between the use of bovhyalu-ronidaze azoximer and the frequency of postoperative complications. We also concluded that there is no statistical relationship between the type of surgery and the frequency of postoperative complications. Based on the results of our pilot study we recommended to conduct a blind randomized placebo-controlled clinical trial of the use of bovhyaluronidaze azoximer treatment form in the urological practice of companion animals.

послеоперационные осложнения, профилактика, катетеризация, цистотомия, уретростомия, бовгиалуронидаза азоксимер, статистическая обработка, avoiding complications, catheterization, cystotomy, perineal urethrostomy, bovgialu-ronidaza azoksimer, statistical processing

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