Changes in the hematological profile of cows under stress caused by pathologies of the limbs

Studies, according to the tasks, were to study changes in the hemato1ogica1, biochemica1, endocrino1ogica1 profi1e of cows with diseases of the 1imbs in comparison with c1inica11y hea1thy. The experimenta1 part of the work was carried out in the SEC "Vyshgorodsky" Ryazan region, Ryazan region, 1aboratory studies were carried out at the Department of veterinary and sanitary examination, surgery, obstetrics and interna1 diseases of anima1s FGBOU V RGATU. The resu1ts presented in the paper indicate that cows due to diseases of the 1imbs, espe-cia11y septic nature, there is a stress reaction, characterized by a deviation of the main b1ood parameters. The most striking changes were observed in the indicators of white b1ood. For examp1e, the number of white b1ood ce11s was higher than in hea1thy cows by an average of 26 %. In the biochemica! profi1e of sick cows noted a decrease in a1-bumin by an average of 30 %, whi1e maintaining the overa11 amount of totat protein. Despite the increase in the tota1 number of 1eukocytes, there were signs of immunosuppressive state, which were expressed in a decrease in 1ymphocytes by an average of 20 %. Indicators of endocrino1ogica1 profi1e c1ear1y reflected the course of the stress reaction in sick cows. This was ref1ected in an increase in cortiso1, more than 80% and thyroxine on average in the group by 35 %. It is important to note that in the 1eukogram in cows with septic 1esions of the 1imbs, we observed monocytosis. During the research we found that anima1s with c1inica11y severe c1audication on the background of patho1ogies of the 1imbs for a 1ong time, experience stress, are exposed in subsequent immunosuppressive condition, which is hard to come subsequent, which is manifested by changes in c1inica1, biochemi-ca1 parameters of b1ood and their c1inica1 condition.

гематологический профиль, биохимический профиль, эндокринологические показатели, лейкограмма, заболевания конечностей, стресс-реакция, hematological profile, biochemical profile, endocrine indices, leu-kogram, diseases of the limbs of the stress response

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