Efficacy of the drug in subclinical mastitis in cows

Abstract

During the research work the spread of subclinical mastitis in the studied farms was established, the microbial factor of pathology development was revealed, the therapeutic efficiency of chlorophyllipt solutions in the treatment of subclinical mastitis in cows was studied. The object of research was Holstein dairy cows with a diagnosis of subclinical mastitis. They were divided on the principle of analogues (by weight, age, 2-3 lactation, breed) into three experimental and fourth control group. For the treatment of subclinical mastitis, the following dosage forms were used: 1% alcohol solution of chlorophyllipt, 1% oil solution of chlorophyllipt, 2% oil solution of chlorophyllipt. There was no treatment in the control group. Drugs were introduced interstitial in an amount of 10 ml 2 times daily after each milking for 3 days. Studying the therapeutic efficacy of chlorophyllipt solutions, it was found that the most effective of the proposed local remedies for subclinical mastitis in cows was a 2% oil solution of chlorophyllipt, the effectiveness of which in the studied farms was 86.6%. the number of somatic cells by the 4th day decreased by 69.8% and amounted to 260.2 thousand, microbial contamination to the 4th day of the experience amounted to 1.15*10 colony forming units per cm3. On the 5th day of the trial period, no inhibitory substances were found in milk, and the number of mesophilic aerobic and facultatively anaerobic microorganisms amounted to 0.85*10 colonies forming units per cm3, which corresponded to the state standard № 31449-2013 "Raw cow's milk".