The effectiveness of ovulation synchronization in the treatment and prevention of infertility in cows

The article presents the results of a study of the effect of gonadotropin-releasing hormone on the restoration of ovarian reproductive function in cows with ovarian hypofunction. In addition, the article describes the effectiveness of ovulation synchronization depending on the stage of the sexual cycle. The aim of the study was to determine the reasons for the effectiveness of using gonadotropin-releasing hormone to synchronize ovulation in cows. The objectives of the study were to determine the ovulatory response to the administration of gonadotropin -releasing hormone during various periods of the sexual cycle and during ovarian hypofunction, as well as hormonal changes during its use. Scientific novelty: for the first time, synchronous clinical and gynecological, ultrasound and radioimmunological studies have been conducted, which reflect changes in the state of the ovaries and in blood hormonal analyses. Results: data on the manifestation of ovulation depending on the state of the ovaries and the long-term consequences of the administration of gonadotropin-releasing hormone, if the timing of its use is determined incorrectly, are presented. With the introduction of gonadotropinreleasing hormone, the lowest percentage of ovulation is observed when it is introduced into the phase of a functionally active corpus luteum. The maximum effect was observed during the end of the sexual cycle and complete involution of the corpus luteum. There was a period of absence of ovulation in the middle of the sexual cycle. Changes in the hormonal background in the blood of cows with the introduction of gonadotropinreleasing hormone, which allow controlling the ovulation process, are described. The regularity of clinical, hematological, and radioimmunological blood tests to determine the hormonal background and control the ultrasound use of the ovaries in determining the state of folliculogenesis in the ovaries of cows with a diagnosis of ovarian hypofunction was noted. Consequently, with the introduction of gonadotropin-releasing hormone, the effect of ovulation is observed with the physiological maturity of the structures and the preserved hormone-synthesizing function of the ovaries.

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