Age-related histological features of the kidneys of the sable of the black pushkin breed

The sable of the black Pushkin breed is an outstanding achievement of breeders in the field of animal husbandry. Its biological features, formed as a result of targeted breeding, ensure the production of skins with unique qualities: deep black color, high density, silkiness and shine. The purpose of the study was to study the histological features of the kidneys of males and females of the black Pushkin breed in the age aspect, as well as to determine their morphometric parameters, and analyze the data obtained. Kidney samples were subjected to histological examination. The material was fixed in a 10% solution of neutral formalin for 24 hours, after which it was poured into paraffin according to the generally accepted method. Then sections 5-7 microns thick were made, which were stained. The analysis of the presented morphometric data on the age-related features of the kidneys in the studied individuals makes it possible to identify clear patterns of growth of all the studied structures with age, as well as minor sex differences. According to all the parameters studied, there is a statistically significant increase in values in animals of the second age group compared with the first. This applies both to the thickness of the general layers of the organ (capsule, cortical and cerebral layer) and microscopic structures (tubule epithelium, vascular glomerulus, renal corpuscle, collecting tubules). This growth is a natural consequence of the general somatic development and maturation of the body. An increase in the thickness of parenchymal layers (cortical and cerebral) is associated with the ongoing process of growth and differentiation of nephrons in the postnatal period, an increase in the size of renal tubules and glomeruli. An increase in the diameter of the vascular glomerulus and the renal corpuscle indicates the development of a filtration apparatus, which corresponds to an increase in the level of metabolism and the need for more intensive blood purification in adults. The thickening of the kidney capsule and the walls of the tubules (single-layered cubic epithelium) also reflects the structural strengthening of the organ during ontogenesis. Also, in both age groups, the absolute values of the morphometric parameters of these structures in males consistently exceed the parameters of females. This difference can be traced both in 15-20-month-old animals and at the age of 36-40 months.

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