Medical treatment of guttural pouch mycosis in horses

Mycosis of the air-bearing SAC is an infectious chronic disease of horses, characterized by nasal discharge and bleeding, various neuropathies; and the main danger of which is the possibility of lethal epistaxis. Fungi of the genus Aspergillus enter the cavity of the bags with inhaled air and settle on the mucosa, damaging the large arterial vessels (internal and external carotid arteries) and nerves (facial, lingopharyngeal, vagus and hypoglossal cranial nerves) running along its surface. The recommended treatment is surgery on the carotid arteries. However, in a stable environment, conservative treatment is safer. This paper provides an overview of effective drug therapy regimens for mycosis of the equine air SAC. For successful elimination of the pathogen, it is necessary to occlude the affected vessels to limit the nutrition of the fungus. However, such surgical techniques are accompanied by a huge risk, require expensive supplies, a sterile operating room and a highly qualified veterinarian. The effectiveness of conservative treatment consists of two components: mechanical action on the fungus in order to separate it and antimycotic therapy, taking into account the sensitivity of the species to the antibiotic. Daily flushing of the air bag with an endoscope at the site of the lesion can soften the diphtheria membrane, which will later allow it to be separated from the wall using biopsy forceps or a cytological brush. The relevance of the work is that it is easier and safer to carry out conservative treatment of mycosis of the air bag in stables. The purpose of this work is to review effective treatment regimens for mycosis of the equine air SAC without surgical intervention. So, we can call the treatment regimen Itraconazole priority, because this drug has been widely studied on horses and has a high activity to fungi of the genus Aspergillus.

микоз воздухоносного мешка, лошади, антимикотики, инфекция, верхние дыхательные пути, Guttural pouch mycosis, horses, antifungals, infection, upper airways

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