Application of "Anestophol 1%" preparation for anesthesia in dogs

Clinical trials of the drug "Anestofol 1%" were conducted in the clinic of the Department of Surgery at the Vitebsk State Academy of Veterinary Medicine. For theresearch the drug "Anestofol 1%" was used for short-term anesthesia with the purpose to conduct diagnostic and small surgical operations in dogs. During clinical trials, three groups of animals were formed based on analogues principlewith the total number of 6 dogs, 2 dogs in each group. For the animals in the first group the drug "Anestofol 1%" was administered intravenously according to the instructions without the use of premedication but with a preliminary infusion of isotonic sodium chloride solution intravenously. The animals of the second group had premedication with a muscle relaxant "Xyla", and then according to the instructions the drug "Anestofol 1%" was administered intravenously. For the animal in the third group the drug "Anestofol 1%" was applied according to the approved instructions without the use of premedication and intravenous infusion of isotonic sodium chloride solution. The experimental animals were the dogs belonging to the vivarium of the VSAVM. Clinical trials showed that during introductory induction with the drug "Anestofol 1%" in dogs of all groups we observed slight changes in the heart rate (HR), particularly, a persistent tendency to decrease especially in the 2nd group where the preparation "Xyla" as a premedication drug was used. Our trialsshowed that the induction dose of this drug should not exceed 8 mg / kg of body weight. The use of the drug "Anestofol-1%"in compliance with the instructions causes a short-term anesthesia that lasts up to 10 - 15 minutes.

собаки, наркоз, препарат, клиника, индукция, внутривенная инъекция, dog, anesthesia, medication, hospital, induction, intravenous injection

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