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Study of the effect of the treatment of parvovirus enteritis on the immunobiochemical reactivity of dogs

Abstract

Researches were conducted to assess the therapeutic effectiveness ofthe parvovirus enteritis treatmentscheme applied in one of veterinary clinics in Omsk.For an experiment 10 dogswere selected: age from 8 to 12 months, 5 clinically healthy (control) and 5 animals with clinical signs of the disease (the vomiting expressed till the end of a disease and hemorrhagic enteritis with a fetid smell).The diagnosis is also confirmed by the results of hematological examination (leukopenia) and chromatographic immunochemical analysis of excrements samples.At the initial admission of the animal, as well as on the 5th day of treatment, blood was taken to assess the biochemical parameters and parameters of nonspecific resistance. According to the results of research in the nitro-blue tetrazolium test the dogs with parvovirus enteritis had a violation of protein and carbohydrate metabolism, as well as inhibition of the production of cationic proteins and active forms of oxygen in neutrophils.As a result of the applied treatmentschemewith etiotropic, pathogenetic and symptomatic therapy, on the 5th day a tendency towards normalization of biochemical indices was noted, as well as restoration of the parameters of non-specific resistance of the organism to the level of healthy dogs.Clinically, the animals treated showed the improvement in the general condition, the appearance of weak appetite, the absence of vomiting and diarrhea.Thus, on the basis of the revealed changes in the parameters of nonspecific resistance and biochemical blood parameters on the 5th day after the start of treatment, the high therapeutic efficacy of using this scheme was shown.

About the Authors

V. . Vlasenko
FGBNU "Omsk Agricultural Research Center"
Russian Federation


E. . Borisov
FGBNU "Omsk Agricultural Research Center"
Russian Federation


N. . Shevyakova
FSBEI HE Omsk sAu
Russian Federation


A. S. Kisil
St. Petersburg State Academy of Veterinary Medicine
Russian Federation


Yu. Yu. Danko
St. Petersburg State Academy of Veterinary Medicine
Russian Federation


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Review

For citations:


Vlasenko V., Borisov E., Shevyakova N., Kisil A.S., Danko Yu.Yu. Study of the effect of the treatment of parvovirus enteritis on the immunobiochemical reactivity of dogs. International Journal of Veterinary Medicine. 2019;(1):21-25. (In Russ.)

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ISSN 2072-2419 (Print)