Diagnostic value of leukocyte indices in animals

Abstract

The aim of the study is to study the diagnostic value of the main leukocyte indices. The study included dogs (n=20 in each group) of different ages with severe manifestations of hepatopathy (acute hepatitis, reactive hepatitis and liver tumors). The control group consisted of clinically healthy dogs without pa thology of the homeostasis system. All animals were analyzed General clinical blood test. Absolute and relative leukocyte counts were assessed by the standard method. From leucoformula calculated leukocyte index. Statistical processing of the material was carried out using Microsoft Excel software package. As a result of the studies, a significant increase in the leukocyte intoxication index was found in all studied hepatopathies. This indicates a pronounced endogenous intoxication, and also shows the presence of a bacterial component. This is extremely important in the evaluation of reactive hepatitis, because in most cases it is extremely difficult to assess due to the fact that the biochemical parameters of blood change slightly or may be within the normative values. Also, an increase in the index of blood leukocyte shift indicates a violation of immunological reactivity in the studied hepatopathies. Based on the data obtained, it can be said that hematological indices (leukocyte intoxication index (LII), blood leukocyte shift index (BLSI) and leukocyte index (LI)) allow to estimate the level of endogenous intoxication of the body, as well as the state of homeostasis. The index of blood leukocyte shift makes it possible to judge the presence of an inflammatory process in the body. This all points to the value of leukocyte indices as a diagnostic method.