About the peculiarities of the organization of the immune system of jawless and jawless fish
https://doi.org/10.52419/issn2072-2419.2026.1.291
Abstract
The immune system of fish, as the first vertebrates to possess all the main components of adaptive immunity, is of considerable interest for comparative immunology. In fish, as in other vertebrates, the immune system provides protection against a variety of pathogens; however, due to the peculiarities of their habitat, they have distinctive immune response properties. The organization of the immune system of fish is an important stage in the evolution of higher vertebrates, thus reflecting the idea of the formation of immunity in higher vertebrates. The review systematizes current data on the evolution, structure, and functioning of immunity in jawless and jawless fish. The aim of the work was to analyze and discuss existing knowledge about the role of various organs and individual genes involved in the defense mechanism of jawless and jawless fish, based on which it is possible to form an idea of evolutionary changes in the immune system of fish. Fish immunity is a complex system that depends on many factors, such as environmental conditions and genetics. Knowledge of the mechanisms of fish immune defense is fundamental to understanding the evolution of the vertebrate immune system and is the basis for developing effective strategies in aquaculture, for example, to create vaccines and immune stimulants. A comparative analysis of modern literature data was carried out, in which studies reflecting the characteristics of the immune response in fish were carefully selected. The results of the generalization are necessary for further study of the resistance of aquaculture facilities to various pathogens in order to grow commercial fish safe for humans.
About the Authors
M. N. Kiseleva
Санкт-Петербургский филиал ГНЦ РФ ФГБНУ «ВНИРО»
Russian Federation
Russian Federation
graduate student
D. K. Mitryushkina
St. Petersburg branch of the State Scientific Center of the Russian Federation FGBNU “VNIRO”
Russian Federation
Russian Federation
graduate student
Yu. N. Lukina
St. Petersburg branch of the State Scientific Center of the Russian Federation FGBNU “VNIRO”;
Institute of Water Problems of the North KarRC RAS
Russian Federation
Russian Federation
Doctor of Biological Sciences, Institute Director
O. V. Apalikova
St. Petersburg branch of the State Scientific Center of the Russian Federation FGBNU “VNIRO”
Russian Federation
Russian Federation
Candidate of Biological Sciences, Head of the Genetics Lab
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Review
For citations:
Kiseleva M.N., Mitryushkina D.K., Lukina Yu.N., Apalikova O.V. About the peculiarities of the organization of the immune system of jawless and jawless fish. International Journal of Veterinary Medicine. 2026;(1):291-301. (In Russ.) https://doi.org/10.52419/issn2072-2419.2026.1.291
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