Application of the drug «IVERSAN» for treatment gasterophilosis of horses

Abstract

The purpose of the work was to study the grag Iversan, containing 40.0 mg of ivermectin in 1.0 ml against equine gasterophilosis. Three groups of naturally infested horses were formed. Animals were of various breeds, from 200 to 600 kg, from 12 months to 17 years. Eggs and larvae of Gasterophilus botfly were detected visually. Animals from Group 1 were given the solution at a dose of 1 ml per 200 kg of body weight (200 μg ivermectin per 1 kg of animal weight) individually, orally with water from a syringe along the margo interalveolaris on the base of tongue. Horses of Group 2 were given the drug with feed individually, once, in the same dose which was calculated individually and mixed with a small amount of oats (50-70 g). The horses of the control group (3) did not received the drug. Before the solution administration and 10 days after animals of experimental groups (1 and 2) were blood sampled. Within 14 days after the drug was used, oral cavity mucous membranes of horses had been examined. It was found that tested solution used orally, once, has a pronounced therapeutic effect against equine gasterophilosis. No itching, irritation or swelling of the skin and mucous membranes, no hyperemia and other signs of an allergic reaction of the organism were found. The drug had no side effects, which was confirmed by the results of clinical blood test and blood chemistry of animals.